Improving the efficacy of antibody-based cancer therapies

Nature Reviews. Cancer
P Carter

Abstract

A quarter of a century after their advent, monoclonal antibodies have become the most rapidly expanding class of pharmaceuticals for treating a wide variety of human diseases, including cancer. Although antibodies have yet to achieve the ultimate goal of curing cancer, many innovative approaches stand poised to improve the efficacy of antibody-based therapies.

References

Mar 1, 1979·Proceedings of the National Academy of Sciences of the United States of America·M HerlynH Koprowski
May 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·P CarterH M Shepard
Oct 1, 1992·The Journal of Experimental Medicine·P C CaronD A Scheinberg
Apr 15, 1992·Proceedings of the National Academy of Sciences of the United States of America·S M RybakR J Youle
Dec 1, 1991·International Clinical Psychopharmacology·S W Burton
May 1, 1991·Medical Physics·S J GoetschB R Thomadsen
Jun 1, 1991·Immunological Reviews·P F LifeJ S Gaston
Mar 25, 1988·Science·M VerhoeyenG Winter
Mar 24, 1988·Nature·L RiechmannG Winter
Dec 13, 1984·Nature·G L BoulianneM J Shulman
Nov 1, 1984·Proceedings of the National Academy of Sciences of the United States of America·S L MorrisonV T Oi
Oct 1, 1993·Proceedings of the National Academy of Sciences of the United States of America·F J Burrows, P E Thorpe
Oct 1, 1994·Current Opinion in Immunology·J G Jurcic, D A Scheinberg
Mar 3, 1995·Science·D D Lasic, D Papahadjopoulos
Feb 28, 1995·Proceedings of the National Academy of Sciences of the United States of America·J W ParkW I Wood
Mar 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J BaselgaL Norton
Jan 1, 1996·Acta Oncologica·M R Zalutsky, D D Bigner
Jul 1, 1996·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M S KaminskiR L Wahl
Aug 6, 1996·Proceedings of the National Academy of Sciences of the United States of America·C LiuR V Chari
Jan 1, 1997·Trends in Biotechnology·A Wright, S L Morrison
Feb 1, 1997·Endocrine Reviews·N Ferrara, T Davis-Smyth
Feb 1, 1997·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·H S StoldtJ G Geraghty
Jul 8, 1997·Proceedings of the National Academy of Sciences of the United States of America·M A GhetieE S Vitetta
Jan 1, 1997·Advances in Pharmacology·J W ParkC C Benz
Jun 1, 1997·Immunotechnology : an International Journal of Immunological Engineering·A Plückthun, P Pack
Aug 1, 1997·Cancer Immunology, Immunotherapy : CII·G A PieterszI F McKenzie
Dec 12, 1997·Biochimica Et Biophysica Acta·I Pastan
Jan 22, 1998·Proceedings of the National Academy of Sciences of the United States of America·R ClynesJ V Ravetch
Feb 12, 1998·Cancer Letters·J W ParkC C Benz
May 20, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G RiethmüllerR Pichlmayr

❮ Previous
Next ❯

Citations

May 21, 2005·Journal of Gastroenterology·Levan AtanelovChristopher Lee
Jun 8, 2007·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Bin LiuJames D Marks
Jun 20, 2007·Journal of Cancer Research and Clinical Oncology·Hyuk-Joon LeeHan-Kwang Yang
Dec 13, 2005·Annals of Biomedical Engineering·Gregory Z FerlJoseph J DiStefano
Feb 15, 2008·Annals of Biomedical Engineering·G HaririD Hallahan
Sep 27, 2008·Breast Cancer Research and Treatment·Juliane WitthauerBarbara Mayer
Jan 13, 2006·Cancer Metastasis Reviews·Jeffrey S RossNeil H Bander
Jan 13, 2006·Cancer Metastasis Reviews·Manuel J KoppeOtto C Boerman
Feb 14, 2009·Cellular and Molecular Neurobiology·Eva KontsekovaMichal Novak
Nov 13, 2008·Cytotechnology·Makiko YamashitaSanetaka Shirahata
Oct 19, 2011·Investigational New Drugs·Marlein Miranda ConaYicheng Ni
Mar 9, 2012·Journal of Pharmacokinetics and Pharmacodynamics·Ben-Fillippo KrippendorffWilhelm Huisinga
Jun 29, 2012·Pharmaceutical Research·Kedan Lin, Jay Tibbitts
Jun 1, 2010·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Kentaro Otani, Kenichi Yamahara
Mar 30, 2013·Molecular Imaging and Biology : MIB : the Official Publication of the Academy of Molecular Imaging·Kentaro Otani, Kenichi Yamahara
Jan 19, 2013·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Philippe Fournier, Volker Schirrmacher
Sep 11, 2013·BioDrugs : Clinical Immunotherapeutics, Biopharmaceuticals and Gene Therapy·Dafne Müller
Jan 10, 2013·Clinical Pharmacokinetics·Miroslav DostalekManoranjenni Chetty
Mar 27, 2013·Molecular Diagnosis & Therapy·Diana P EnglishAlessandro D Santin
Jun 16, 2005·Bioorganic & Medicinal Chemistry·Stanislav JaraczIwao Ojima
Apr 23, 2004·Trends in Immunology·Laura SanzLuis Alvarez-Vallina
Mar 24, 2004·Trends in Immunology·Kyra A GeldermanArko Gorter
Apr 19, 2005·Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences·Alain BeckJean-François Haeuw
Jun 20, 2003·Progress in Lipid Research·P Sapra, T M Allen
Dec 17, 2002·Current Opinion in Biotechnology·Mohit TrikhaMarian T Nakada
Dec 6, 2012·Journal of the American Chemical Society·Stephanie A KazaneVaughn V Smider
May 21, 2003·Breast Cancer Research and Treatment·Tero A H Järvinen, Edison T Liu
Mar 30, 2007·Nature Clinical Practice. Oncology·Alejandro D Ricart, Anthony W Tolcher
Jan 7, 2003·Nature Medicine·Peter J Hudson, Christelle Souriau
Jul 26, 2008·Nature Nanotechnology·Dan PeerRobert Langer
Aug 25, 2006·Nature Reviews. Cancer·Kohzoh Imai, Akinori Takaoka
May 13, 2008·Nature Reviews. Cancer·Klaus Strebhardt, Axel Ullrich
Oct 3, 2002·Nature Reviews. Cancer·Theresa M Allen
Jan 21, 2006·Nature Reviews. Drug Discovery·David SchramaJürgen C Becker
Apr 14, 2007·Nature Reviews. Drug Discovery·Janice M Reichert, Viia E Valge-Archer
Apr 20, 2006·Nature Reviews. Immunology·Paul J Carter
Feb 13, 2013·Nature Reviews. Rheumatology·Pauline A van SchouwenburgGerrit Jan Wolbink

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