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Improving the gene-regulation ability of small RNAs by scaffold engineering in Escherichia coli

ACS Synthetic Biology

Mar 21, 2014

Yuta SakaiKazunori Ikebukuro

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Abstract

Noncoding small RNAs are involved in transcriptional and post-transcriptional gene regulation of target mRNAs by modulating mRNA elongation, stability, or translational efficiency. Many natural trans-encoded small RNAs contain a scaffold that allows binding of the RNA chaperone protein ...read more

Mentioned in this Paper

Gene Expression
Terminator Regions, Genetic
RNA
Genetic Translation Process
RNA, Small Untranslated
RNA Conformation
Escherichia coli
Genetic Engineering
Synthetic Biology
Alkalescens-Dispar Group
2
1
64
Paper Details
References
  • References33
  • Citations13
1234
  • References33
  • Citations13
12

Improving the gene-regulation ability of small RNAs by scaffold engineering in Escherichia coli

ACS Synthetic Biology

Mar 21, 2014

Yuta SakaiKazunori Ikebukuro

PMID: 24328142

DOI: 10.1021/sb4000959

Abstract

Noncoding small RNAs are involved in transcriptional and post-transcriptional gene regulation of target mRNAs by modulating mRNA elongation, stability, or translational efficiency. Many natural trans-encoded small RNAs contain a scaffold that allows binding of the RNA chaperone protein ...read more

Mentioned in this Paper

Gene Expression
Terminator Regions, Genetic
RNA
Genetic Translation Process
RNA, Small Untranslated
2
1
64
Paper Details
References
  • References33
  • Citations13
1234
  • References33
  • Citations13
12

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