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Improving the gene-regulation ability of small RNAs by scaffold engineering in Escherichia coli

ACS Synthetic Biology

Dec 18, 2013

Yuta SakaiKazunori Ikebukuro

Abstract

Noncoding small RNAs are involved in transcriptional and post-transcriptional gene regulation of target mRNAs by modulating mRNA elongation, stability, or translational efficiency. Many natural trans-encoded small RNAs contain a scaffold that allows binding of the RNA chaperone protein ...read more

Mentioned in this Paper

Gene Expression Regulation, Bacterial
RNA Conformation
Alkalescens-Dispar Group
Transcription, Genetic
Gene Expression
RNA Chaperone
Terminator Regions, Genetic
Genetic Translation Process
Escherichia coli
Synthetic Biology
2
1
65
Paper Details
References
  • References33
  • Citations14
1234
  • References33
  • Citations14
12

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Improving the gene-regulation ability of small RNAs by scaffold engineering in Escherichia coli

ACS Synthetic Biology

Dec 18, 2013

Yuta SakaiKazunori Ikebukuro

PMID: 24328142

DOI: 10.1021/sb4000959

Abstract

Noncoding small RNAs are involved in transcriptional and post-transcriptional gene regulation of target mRNAs by modulating mRNA elongation, stability, or translational efficiency. Many natural trans-encoded small RNAs contain a scaffold that allows binding of the RNA chaperone protein ...read more

Mentioned in this Paper

Gene Expression Regulation, Bacterial
RNA Conformation
Alkalescens-Dispar Group
Transcription, Genetic
Gene Expression
RNA Chaperone
Terminator Regions, Genetic
Genetic Translation Process
Escherichia coli
Synthetic Biology
2
1
65

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Epigenome Engineering

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RNA

Role of polynucleotide phosphorylase in sRNA function in Escherichia coli

RNAApril 30, 2011
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Positive regulation by small RNAs and the role of Hfq

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Paper Details
References
  • References33
  • Citations14
1234
  • References33
  • Citations14
12
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