Improving the precision of depression diagnosis in general practice: a cluster-randomized trial.

BMC Family Practice
Ursula Ødum Brinck-ClaussenLene Falgaard Eplov

Abstract

Methods to enhance the accuracy of the depression diagnosis continues to be of relevance to clinicians. The primary aim of this study was to compare the diagnostic precision of two different diagnostic strategies using the Mini International Neuropsychiatric Interview (MINI) as a reference standard. A secondary aim was to evaluate accordance between depression severity found via MINI and mean Major Depression Inventory (MDI) sum-scores presented at referral. This study was a two-armed, cluster-randomized superiority trial embedded in the Collabri trials investigating collaborative care in Danish general practices. GPs performing case-finding were instructed always to use MDI when suspecting depression. GPs performing usual clinical assessment were instructed to detect depression as they would normally do. According to guidelines, GPs would use MDI if they had a clinical suspicion, and patients responded positively to two or three core symptoms of depression. We compared the positive predictive value (PPV) in the two groups. Fifty-one GP clusters were randomized. In total, 244 participants were recruited in the case-finding group from a total of 19 GP clusters, and 256 participants were recruited in the usual clinical assessment...Continue Reading

Associated Clinical Trials

Feb 10, 2016·Lene Falgaard Eplov

References

Jun 28, 2003·International Journal of Methods in Psychiatric Research·Kurt Kroenke
Jan 17, 2004·Acta Psychiatrica Scandinavica·L R OlsenP Bech
Oct 20, 2005·The Cochrane Database of Systematic Reviews·S GilbodyT A Sheldon
May 2, 2009·The British Journal of Psychiatry : the Journal of Mental Science·Kim D BaasAart H Schene
Jul 31, 2009·Lancet·Alex J MitchellSanjay Rao
May 6, 2011·Scandinavian Journal of Primary Health Care·Kaj Sparle ChristensenFrede Olesen
Oct 19, 2012·The Cochrane Database of Systematic Reviews·Janine ArcherPeter Coventry
Nov 11, 2014·International Journal of Qualitative Studies on Health and Well-being·Annette S Davidsen, Christina F Fosgerau
Sep 9, 2015·Neuropsychiatric Disease and Treatment·Ching-I HungChing-Hui Yang
Jan 28, 2016·JAMA : the Journal of the American Medical Association·Albert L SiuMichael P Pignone
Jul 25, 2017·Trials·Ursula Ødum Brinck-ClaussenLene Falgaard Eplov

❮ Previous
Next ❯

Software Mentioned

STATA
/ SE

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.