Improving topical microbicide applicators for use in resource-poor settings

American Journal of Public Health
Janet G VailKimberly L Kelly

Abstract

With more than 60 potential microbicides being assessed in preclinical or clinical trials, most attention has been centered on products intended for topical application, with much less research conducted on the applicators that will be used to deliver the microbicides. However, applicator design relates to safety, efficacy, and acceptability. As the foundation for a more systematic approach to evaluating and possibly improving designs for topical microbicide applicators, we conducted a literature review and a series of interviews with microbicide developers, trial investigators, and trial sponsors. Our findings indicate that issues concerning applicator safety, reuse, and cost warrant further investigation.

References

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Jan 28, 2003·Health Services Research·Kathryn A PhillipsF Reed Johnson

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Citations

May 13, 2006·Sexually Transmitted Diseases·Jessica A CohenMags E Beksinska
Feb 28, 2007·Journal of Acquired Immune Deficiency Syndromes : JAIDS·Kathleen M MorrowLawrence Severy
Sep 18, 2014·Journal of Controlled Release : Official Journal of the Controlled Release Society·Rute NunesJosé das Neves
Feb 24, 2015·Advanced Drug Delivery Reviews·Cynthia Woodsong, Jonathon D S Holt
Dec 19, 2009·Pharmaceutical Development and Technology·David R Friend
May 9, 2021·Scientific Reports·Alyssa J BakkeJohn E Hayes

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