Aug 13, 2013

Improving vital organs perfusion by the respiratory pump: physiology and clinical use

Annales Françaises D'anesthèsie Et De Rèanimation
Nicolas SegalV A Convertino

Abstract

In this article, we review the effects of the respiratory pump to improve vital organ perfusion by the use of an inspiratory threshold device. Medline and MeSH database. All papers with a level of proof of I to III have been used. The analysis of the papers has focused on the physiological modifications induced by intrathoracic pressure regulation. Primary function of breathing is to provide gas exchange. Studies of the mechanisms involved in animals and humans provide the physiological underpinnings for "the other side of breathing": to increase circulation to the heart and brain. We describe studies that focus on the fundamental relationship between the generation of negative intrathoracic pressure during inspiration through a low-level of resistance created by an impedance threshold device and the physiologic effects of a respiratory pump. A decrease in intrathoracic pressure during inspiration through a fixed resistance resulting in an intrathoracic pressure of -7 cmH2O has multiple physiological benefits including: enhanced venous return, cardiac stroke volume and aortic blood pressure; lower intracranial pressure; resetting of the cardiac baroreflex; elevated cerebral blood flow oscillations and increased tissue blood flo...Continue Reading

  • References37
  • Citations2

References

Mentioned in this Paper

Cerebral Blood Flow Imaging
Plethysmography, Impedance
Electric Impedance
Airway Resistance
Regional Blood Flow
Hypotension, Orthostatic
Blood Flow
Organ
Cerebrovascular Accident
Aorta

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