IMRT delivery performance with a varian multileaf collimator

International Journal of Radiation Oncology, Biology, Physics
T LoSasso

Abstract

The use of a multileaf collimator (MLC) for intensity-modulated radiotherapy poses unique dosimetric issues. The nature of intensity-modulated radiotherapy dosimetry, centered on leaf position accuracy, is common to all MLCs. However, the mechanical and software designs of MLCs from the different manufacturers distinguish them. This report focused on the Varian Millennium 120, although the concepts are applicable to the earlier Varian Mark series as well. The factors that affect dose delivery in clinical fields (i.e., mechanical tolerances, motor fatigue, and latency effects) have been quantified. Moreover, inadequate modeling of the MLC in the planning system can be perceived as erratic performance. Individually, some problems have been shown to be insignificant; others are correctable using software. If these problems are rectified or at least understood by the physicist, quality assurance can be simplified.

References

May 1, 1996·Medical Physics·C S ChuiT LoSasso
Mar 1, 1996·Medical Physics·X WangB Mohan
Oct 1, 1996·Physics in Medicine and Biology·J P van Santvoort, B J Heijmen
Aug 16, 2000·Physics in Medicine and Biology·Q WuR Mohan
Apr 28, 2001·Physics in Medicine and Biology·J DengC M Ma
Jul 6, 2001·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·M EssersB J Heijmen
May 30, 2002·Medical Physics·Dale W LitzenbergBenedick A Fraass
Aug 17, 2002·International Journal of Radiation Oncology, Biology, Physics·Linda HongSteve Leibel
Mar 12, 2004·Physics in Medicine and Biology·Srijit KamathJonathan Li
May 22, 2004·Physics in Medicine and Biology·Yong Yang, Lei Xing
Oct 9, 2004·Physics in Medicine and Biology·P TangboonduangjitA Rosenfeld

❮ Previous
Next ❯

Citations

Oct 9, 2012·Medical Physics·Pejman RowshanfarzadPeter B Greer
Dec 20, 2011·Seminars in Radiation Oncology·Benedick A Fraass, Jean M Moran
Sep 29, 2011·Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists·Nathalie Fournier-BidozAlain Fourquet
Sep 8, 2010·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Mike OliverWayne Beckham
Oct 3, 2015·Medical Physics·Tobias EckhauseJean M Moran
Oct 9, 2009·Medical Physics·Eric E KleinUNKNOWN Task Group 142, American Association of Physicists in Medicine
May 11, 2016·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Yoshiyuki KatsutaKeiichi Jingu
Jan 10, 2017·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·José Olasolo-AlonsoJosé Fernando Pérez-Azorín
Aug 8, 2017·Physics in Medicine and Biology·Kyle J GallagherJunan Zhang
Sep 28, 2018·Australasian Physical & Engineering Sciences in Medicine·Joshua HiattPejman Rowshanfarzad
Aug 13, 2014·Radiation Oncology·James R KernsStephen F Kry
Apr 12, 2019·Medical Physics·Francesca BonfantiniEmanuele Pignoli
Mar 8, 2016·Physics in Medicine and Biology·Joel N K CarlsonSung-Joon Ye
Mar 20, 2019·Journal of Applied Clinical Medical Physics·Tze Yee LimGwe-Ya Kim
Aug 17, 2011·Journal of Applied Clinical Medical Physics·Dayananda Shamurailatpam SharmaMalhotra Heigrujam
Nov 5, 2016·Physics in Medicine and Biology·Damianos ChristophidesMark Fleckney
Sep 30, 2016·Journal of Applied Clinical Medical Physics·Benjamin J ZwanPeter B Greer
Dec 15, 2020·Medical Physics·Victor Gabriel Leandro AlvesJeffrey Vincent Siebers
Sep 14, 2019·Physica Medica : PM : an International Journal Devoted to the Applications of Physics to Medicine and Biology : Official Journal of the Italian Association of Biomedical Physics (AIFB)·Mikaël AntoineJérôme Caron
Jul 20, 2021·Journal of Applied Clinical Medical Physics·Seng Boh LimDale Michael Lovelock
Sep 11, 2021·Journal of Applied Clinical Medical Physics·Ergys SubashiNeelam Tyagi

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.