In an Aboriginal birth cohort, only child size and not birth size, predicts insulin and glucose concentrations in childhood

Diabetes Research and Clinical Practice
Susan M SayersAlison Reid

Abstract

The objectives were to describe cross-sectional growth in 279 Australian Aboriginal children aged 8-14 years in order to test the hypothesis that birth size interacts with child size to predict glucose and insulin metabolism. Cross-sectional growth outcomes were described using standard deviation scores or z-scores for height for age (HAZ) and weight for age (WAZ) calculated from CDC 2000 reference values in Epi Info 2000. Interrelationships were examined using standard regression models with current height and weight and birth weight, ponderal index and birth weight below the 10th percentile for gestational age. All models were adjusted for gestational age, gender and chronological age. Growth outcomes were poor with negative mean z scores for height and weight. Children with a birth weight <10th percentile for gestational age were significantly smaller and lighter than those with a birth >/= 10th percentile for gestational age, indicating post-natal catch-up growth of small babies was unlikely. After adjustment for childhood size, there was no relationship between any birth measures and fasting glucose or insulin concentrations. Current child height and weight had positive relationships with both fasting insulin and glucose c...Continue Reading

References

Feb 1, 1994·The Australian & New Zealand Journal of Obstetrics & Gynaecology·R L GuaranN A Beischer
Aug 1, 1997·Australian and New Zealand Journal of Public Health·S Sayers, J Powers
Jul 23, 1999·BMJ : British Medical Journal·A LucasT J Cole
May 3, 2000·Australian and New Zealand Journal of Public Health·K G RowleyK O'Dea
Jul 25, 2000·Annals of Internal Medicine·T ForsénD Barker
May 20, 2003·Diabetic Medicine : a Journal of the British Diabetic Association·C A NewsomeC M Law

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Citations

Sep 25, 2009·BMC International Health and Human Rights·Susan SayersJoseph Fitz
Dec 8, 2009·Pediatric Clinics of North America·Alan R Ruben
Nov 7, 2006·Social Science & Medicine·Brian G GilesSakakohe Pembleton
Apr 29, 2005·Diabetes/metabolism Research and Reviews

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