In cryptozoospermia or severe oligozoospermia is sperm freezing useful?

Basic and Clinical Andrology
Julien BessonnatSylviane Hennebicq

Abstract

Intracytoplasmic Sperm Injection (ICSI) is an Assisted Reproduction Technique (ART) which offers the chance to conceive to patients presenting very low sperm counts (cryptozoospermia/severe oligozoospermia). Sperm freezing before the oocyte pick-up, can prevent from a lack of spermatozoa on the day of the ICSI. It can avoid the cancellation of the ICSI or the use of TESE (Testicular sperm extraction). The objective of this study was to analyse the practice of sperm freezing for these patients in our center over 8 years and the rate of use of these frozen sperms. We also compared the outcome of ICSIs with frozen versus ejaculated sperm. We performed a retrospective epidemiological study between 2004 and 2011. We recruited all the patients having a sperm count below 1 Million/mL and who were waiting for their first ICSI attempt. 169 patients were recruited: 84 cryopreserved their sperm before the ICSI (secured ICSI) while 85 did not (non-secured ICSI). Both groups were split in cryptozoospermia (<10(3) spermatozoa/ml): 19 and 17 patients respectively, very severe oligozoospermia (10(3)-10(5)/ml): 37 and 13 patients, and severe oligozoospermia (10(5)-10(6)/ml): 28 and 55 patients. The part of secured ICSI significantly increased f...Continue Reading

References

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Citations

Sep 14, 2015·Human Reproduction·M MontagutR Leandri
Dec 21, 2017·Reproductive Medicine and Biology·Itsuto HamanoChikara Ohyama

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Methods Mentioned

BETA
Extraction
density gradient centrifugation

Software Mentioned

R
Excel

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