In depressed older persons higher blood pressure is associated with symptoms of apathy. The NESDO study

International Psychogeriatrics
J E F MoonenR C van der Mast

Abstract

In older persons, a relationship between both higher and lower blood pressure and depression has inconsistently been reported. Blood pressure may be differentially associated with distinct symptom domains of depression. We examined the cross-sectional relation of current systolic blood pressure (SBP), diastolic blood pressure (DBP) and mean arterial pressure (MAP) with different depressive symptom domains among depressed older persons. In the Netherlands Study of Depression in Older Persons (NESDO), 270 participants aged 60 years and above were diagnosed with depression in the past month. Using the three corresponding subscales of the Inventory of Depressive Symptoms-Self Report (IDS-SR), motivational, mood and somatic symptom domains were assessed. Additionally, symptoms of apathy were determined with the Apathy Scale. Multiple linear regression was used to examine the cross-sectional relationship between current SBP, DBP and MAP with both IDS-SR subscale and Apathy Scale scores. Unstandardized betas were calculated per 10 mmHg increase in blood pressure measures. Mean age of participants was 70.4 years (standard deviation 7.3). Higher SBP (Beta 0.33, t (254) = 2.01, p = 0.045), higher DBP (Beta 0.68, t (254) = 2.15, p = 0.03)...Continue Reading

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Citations

Aug 25, 2015·Journal of Stroke and Cerebrovascular Diseases : the Official Journal of National Stroke Association·Hiroshi YaoManabu Hashimoto
Oct 17, 2019·International Journal of Geriatric Psychiatry·Lonneke WoutsRichard C Oude Voshaar
May 1, 2020·Journal of the American Geriatrics Society·Anne Suzanne BertensNathaly Rius Ottenheim
Mar 10, 2020·Oxidative Medicine and Cellular Longevity·Danfeng LinAnwen Shao

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