In-hospital management and outcomes of acute coronary syndromes in relation to prior history of heart failure

European Heart Journal. Acute Cardiovascular Care
Hanfei ZhangCanadian GRACE and CANRACE Investigators

Abstract

The prognostic significance of prior heart failure in acute coronary syndromes has not been well studied. Accordingly, we evaluated the baseline characteristics, management patterns and clinical outcomes in patients with acute coronary syndromes who had prior heart failure. The study population consisted of acute coronary syndrome patients in the Global Registry of Acute Coronary Events, expanded Global Registry of Acute Coronary Events and Canadian Registry of Acute Coronary Events between 1999 and 2008. Of the 13,937 eligible patients (mean age 66±13 years, 33% female and 28.3% with ST-elevation myocardial infarction), 1498 (10.7%) patients had a history of heart failure. Those with prior heart failure tended to be older, female and had lower systolic blood pressure, higher Killip class and creatinine on presentation. Prior heart failure was also associated with significantly worse left ventricular systolic function and lower rates of cardiac catheterization and coronary revascularization. The group with previous heart failure had significantly higher rates of acute decompensated heart failure, cardiogenic shock, myocardial (re)infarction and mortality in hospital. In multivariable analysis, prior heart failure remained an in...Continue Reading

References

Feb 10, 1989·JAMA : the Journal of the American Medical Association·L W Stevenson, J K Perloff
Jun 2, 2001·The New England Journal of Medicine·M PackerUNKNOWN Carvedilol Prospective Randomized Cumulative Survival Study Group
Oct 24, 2002·Journal of the American College of Cardiology·Audrey H WuUNKNOWN Second National Registry of Myocardial Infarction
Sep 19, 2003·Lancet·Marc A PfefferUNKNOWN CHARM Investigators and Committees
Oct 29, 2003·Archives of Internal Medicine·Christopher B GrangerUNKNOWN Global Registry of Acute Coronary Events Investigators
Jan 28, 2004·Circulation·Philippe Gabriel StegUNKNOWN Global Registry of Acute Coronary Events Investigators
Jun 10, 2004·JAMA : the Journal of the American Medical Association·Kim A EagleUNKNOWN GRACE Investigators
Nov 8, 2005·Lancet·Z M ChenUNKNOWN COMMIT (ClOpidogrel and Metoprolol in Myocardial Infarction Trial) collaborative group
Jun 8, 2006·JAMA : the Journal of the American Medical Association·Judith S HochmanUNKNOWN SHOCK Investigators
Jun 13, 2006·The American Journal of Cardiology·Matthew T RoeUNKNOWN CRUSADE Investigators
Oct 3, 2006·Acute Cardiac Care·Zaza IakobishviliUNKNOWN Israeli ACSIS 2004 Investigators
May 3, 2007·JAMA : the Journal of the American Medical Association·Keith A A FoxUNKNOWN GRACE Investigators
Aug 30, 2008·Circulation·Philippe Gabriel StegUNKNOWN Global Registry of Acute Coronary Events (GRACE) Investigators
Nov 13, 2008·European Heart Journal·Putte AbrahamssonUNKNOWN CHARM Investigators
May 22, 2009·The New England Journal of Medicine·Shamir R MehtaUNKNOWN TIMACS Investigators
Jul 22, 2009·American Heart Journal·Shaun G GoodmanUNKNOWN Expanded Global Registry of Acute Coronary Events (GRACE2) Investigators
Apr 7, 2010·American Heart Journal·Sean JedrzkiewiczUNKNOWN Canadian Acute Coronary Syndrome I and II Registries, Canadian Global Registry of Acute Coronary Events (GRACE/GRACE2), and
Aug 17, 2010·European Heart Journal·Demosthenes G KatritsisJohn P A Ioannidis
Apr 14, 2012·European Journal of Heart Failure·Isuru RanasingheUNKNOWN Australia–New Zealand GRACE

❮ Previous
Next ❯

Citations

Apr 19, 2018·Clinical Cardiology·Eva FreisingerKarl Wegscheider
Mar 31, 2017·European Heart Journal. Acute Cardiovascular Care·Nigel S TanUNKNOWN Canadian GRACE/GRACE-2 and CANRACE Investigators

❮ Previous
Next ❯

Methods Mentioned

BETA
coronary bypass

Software Mentioned

GRACE
CANRACE
SPSS

Related Concepts

Related Feeds

Cardiogenic Shock

Cardiogenic shock is a devastating consequence of acute myocardial infarction and is associated with an extremely high mortality. Here is the latest research.

Related Papers

The American Journal of Cardiology
Tony C LeeCanadian Acute Coronary Syndromes I and II, Canadian Global Registry of Acute Coronary Events (GRACE/GRACE2) and the Canadia
The American Journal of Cardiology
Alan J BagnallCanadian Global Registry of Acute Coronary Events (GRACE/GRACE2) Investigators
© 2021 Meta ULC. All rights reserved