In-hospital outcomes after transcatheter or surgical aortic valve replacement in younger patients less than 75 years old: a propensity-matched comparison

EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology
Holger EggebrechtRajendra H Mehta

Abstract

Randomised trials comparing transcatheter aortic valve replacement (TAVR) with surgical aortic valve replacement (SAVR) have included mainly elderly patients >80 years. The authors investigated comparative in-hospital outcomes of younger patients <75 years undergoing transfemoral (TF) TAVR or isolated SAVR. A total of 6,972 patients aged 65-74 years undergoing TF-TAVR or SAVR between 2013 and 2014 were identified from the observational German Quality Assurance Registry on Aortic Valve Replacement (AQUA), which comprises all TAVR and SAVR procedures performed in Germany. Analyses were performed for the overall unmatched cohort as well as for 1,388 propensity-matched patients. Overall, 82.4% of patients <75 years needing treatment for aortic valve stenosis received SAVR. Patients undergoing TF-TAVR were older and had more comorbidities with higher predicted risk of death. After propensity-matching, in-hospital mortality (1.3% vs. 1.9%, p=0.39), neurologic complications (1.0% vs. 2.1%, p=0.09), and myocardial infarctions (0 vs. 0.3%, p=0.16) were not different after TF-TAVR or SAVR. Postoperative delirium was more frequent after SAVR (8.9% vs. 2.4%, p<0.001), whereas the need for new pacemaker was 4 times higher after TF-TAVR (13....Continue Reading

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Citations

Sep 28, 2018·Minerva cardioangiologica·Lucia JunqueraJosep Rodés-Cabau
Apr 9, 2019·Circulation Journal : Official Journal of the Japanese Circulation Society·In-Chang HwangHyo-Soo Kim
Aug 14, 2019·European Heart Journal·Mohamad AlkhouliVerghese Mathew
Apr 18, 2020·Journal of the American Heart Association·Vinayak KumarCharanjit S Rihal
Aug 20, 2019·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Giuseppe TarantiniUNKNOWN OBSERVANT Research Group
Jun 26, 2020·Catheterization and Cardiovascular Interventions : Official Journal of the Society for Cardiac Angiography & Interventions·Yuji MatsudaGiuseppe Tarantini
Dec 16, 2018·Clinical Research in Cardiology : Official Journal of the German Cardiac Society·Derk FrankHelmut Baumgartner
Feb 23, 2019·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·Josephina HaunschildChristian D Etz
Jan 1, 2021·Frontiers in Cardiovascular Medicine·Pier Paolo BocchinoLuigi Biasco
Nov 7, 2020·JACC. Cardiovascular Interventions·Kees van der WulpNiels van Royen

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