In-hospital, short-term and long-term adverse clinical outcomes observed in patients with type 2 diabetes mellitus vs non-diabetes mellitus following percutaneous coronary intervention: A meta-analysis including 139,774 patients

Medicine
Xiaojun ZhuoZhaohui Dai

Abstract

Several studies have shown that patients with type 2 diabetes mellitus (T2DM) have worse clinical outcomes in comparison to patients without diabetes mellitus (DM) following Percutaneous Coronary Intervention (PCI). However, the adverse clinical outcomes were not similarly reported in all the studies. Therefore, in order to standardize this issue, a meta-analysis including 139,774 patients was carried out to compare the in-hospital, short-term (<1 year) and long-term (≥1 year) adverse clinical outcomes in patients with and without T2DM following PCI. Electronic databases including MEDLINE, EMBASE, and the Cochrane Library were searched for Randomized Controlled Trials (RCTs) and observational studies. The adverse clinical outcomes which were analyzed included mortality, myocardial infarction (MI), major adverse cardiac events (MACEs), stroke, bleeding, target vessel revascularization (TVR), target lesion revascularization (TLR), and stent thrombosis. Risk Ratios (RR) with 95% confidence intervals (CI) were used to express the pooled effect on discontinuous variables and the analysis was carried out by RevMan 5.3 software. A total number of 139,774 participants were assessed. Results of this analysis showed that in-hospital mort...Continue Reading

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Citations

Aug 17, 2019·Journal of Biomolecular Structure & Dynamics·Ya-Ya LiuXian-Chao Cheng
Oct 23, 2020·Cardiovascular Drugs and Therapy·Zhe LiangQuanming Zhao
Feb 17, 2021·Neurosurgical Review·Shan-Shan ChuDao-Bao Zhang
Oct 2, 2021·EuroIntervention : Journal of EuroPCR in Collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology·Isabelle JohanssonFrancesco Cosentino

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Methods Mentioned

BETA
Coronary Artery Bypass

Software Mentioned

EVASTENT
RevMan

Related Concepts

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CV Disorders & Type 2 Diabetes

This feed focuses on the association of cardiovascular diseases in patients with type 2 diabetes.