PMID: 9558680Apr 29, 1998Paper

"In-line" bipolar, steroid-eluting, high impedance, epimyocardial pacing lead

Pacing and Clinical Electrophysiology : PACE
P P KarpawichR McVenes

Abstract

Recent advances in electrode surface designs have eliminated traditional threshold differences between endo- and epicardial pacing leads. Since the epicardial approach offers the potential of direct left ventricular pacing and the transvenous approach may not be feasible or warranted in all instances, more advanced leads are being designed to optimize epicardial pacing capabilities. This study was conducted to evaluate a bipolar epimyocardial lead. Six immature canines (age 3 months) were instrumented. The lead (Medtronic model 10389) is a single-pass, "in-line" bipolar electrode with low current drain and high impedance, with an intramyocardial steroid-eluting cathode and nonsteroid epicardial anode. Twelve ventricular leads were implanted (two per animal) and the animals followed for 6 months with weekly analysis of pacing and sensing capabilities. Results at explant were compared with implant values and showed no significant differences between sensed R waves or in R wave slew rates in unipolar or bipolar modes. Explant lead impedances remained high in both modes: bipolar, 1658 +/- 331; and unipolar, 1327 +/- 308 omega (P < 0.05). Chronic voltage (V) threshold at 0.5 ms showed no significant change from implant values during...Continue Reading

References

Nov 1, 1992·Pacing and Clinical Electrophysiology : PACE·P P KarpawichK B Stokes
Aug 11, 1992·Journal of the American College of Cardiology·J A JohnsJ W Hammon
Nov 1, 1991·Pacing and Clinical Electrophysiology : PACE·K B StokesB Gunderson
Nov 1, 1991·Pacing and Clinical Electrophysiology : PACE·P P KarpawichW W Pinsky
Nov 1, 1991·Pacing and Clinical Electrophysiology : PACE·R HamiltonW Williams
Dec 1, 1989·Pacing and Clinical Electrophysiology : PACE·J A GoudevenosD O Williams
Mar 1, 1989·American Heart Journal·J D Kugler, D A Danford
Dec 1, 1971·The American Journal of Physiology·R C Boerth, J W Covell
May 1, 1993·Pacing and Clinical Electrophysiology : PACE·D F OrtegaR Chirife
Nov 1, 1994·Pacing and Clinical Electrophysiology : PACE·P P KarpawichM Factkor

❮ Previous
Next ❯

Citations

Aug 14, 2003·Pacing and Clinical Electrophysiology : PACE·M Silvana HorensteinPeter P Karpawich

❮ Previous
Next ❯

Related Concepts

Related Feeds

Arrhythmia

Arrhythmias are abnormalities in heart rhythms, which can be either too fast or too slow. They can result from abnormalities of the initiation of an impulse or impulse conduction or a combination of both. Here is the latest research on arrhythmias.