In-line treatments and clinical initiatives to fight against COVID-19 outbreak

Respiratory Medicine
Mukta AgrawalAmit Alexander

Abstract

In December 2019, when the whole world is waiting for Christmas and New Year, the physicians of Wuhan, China, are astounded by clusters of patients suffering from pneumonia from unknown causes. The pathogen isolated from the respiratory epithelium of the patients is similar to previously known coronaviruses with some distinct features. The disease was initially called nCoV-2019 or SARS-nCoV-2 and later termed as COVID-19 by WHO. The infection is rapidly propagating from the day of emergence, spread throughout the globe and now became a pandemic which challenged the competencies of developed nations in terms of health care management. As per WHO report, 216 countries are affected with SARS-CoV-19 by August 5, 2020 with 18, 142, 718 confirmed cases and 691,013 deaths reports. Such huge mortality and morbidity rates are truly threatening and calls for some aggressive and effective measures to slow down the disease transmission. The scientists are constantly engaged in finding a potential solution to diagnose and treat the pandemic. Various FDA approved drugs with the previous history of antiviral potency are repurposed for COVID-19 treatment. Different drugs and vaccines are under clinical trials and some rapid and effective diagn...Continue Reading

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Citations

Apr 23, 2021·International Journal of Environmental Health Research·Sima SinghPrashant Kesharwani

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Methods Mentioned

BETA
X-Ray
bronchoalveolar lavage
glycosylation

Clinical Trials Mentioned

NCT04246242
NCT04261270
NCT04264533
NCT04273763
NCT04273646
NCT04304053
NCT04303507
NCT04280588
NCT04264858
NCT04276688

Software Mentioned

Genfit
Romark
Mucokinetica
Gilead
Sciences

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