In silico gene expression profiling in Cannabis sativa

F1000Research
Luca Massimino

Abstract

The cannabis plant and its active ingredients (i.e., cannabinoids and terpenoids) have been socially stigmatized for half a century. Luckily, with more than 430,000 published scientific papers and about 600 ongoing and completed clinical trials, nowadays cannabis is employed for the treatment of many different medical conditions. Nevertheless, even if a large amount of high-throughput functional genomic data exists, most researchers feature a strong background in molecular biology but lack advanced bioinformatics skills. In this work, publicly available gene expression datasets have been analyzed giving rise to a total of 40,224 gene expression profiles taken from cannabis plant tissue at different developmental stages. The resource presented here will provide researchers with a starting point for future investigations with Cannabis sativa.

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Citations

Feb 23, 2019·Journal of the National Cancer Institute·Stuart E SiegelArchie Bleyer
Mar 26, 2020·Physiologia Plantarum·Roberto BerniGea Guerriero
Jul 12, 2017·F1000Research·Luca Massimino

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Datasets Mentioned

BETA
SRP006678
SRP008673
GSE93201

Software Mentioned

GENE
TopHat2
Cufflinks

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