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In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci

Mammalian Genome : Official Journal of the International Mammalian Genome Society

Jan 2, 2015

Darryl L HadsellTimothy C Cox

Abstract

Genetic background plays a dominant role in mammary gland development and breast cancer (BrCa). Despite this, the role of genetics is only partially understood. This study used strain-dependent variation in an inbred mouse mapping panel, to identify quantitative trait loci (QTL) underly...read more

Mentioned in this Paper

Conserved Synteny
Genome-Wide Association Study
In Silico
Quantitative Trait Loci
TBX3 gene
Mammary Tumorigenesis
Genome
Mammary Gland
Mammary Gland Development
Inbred Strain
Paper Details
References
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In-silico QTL mapping of postpubertal mammary ductal development in the mouse uncovers potential human breast cancer risk loci

Mammalian Genome : Official Journal of the International Mammalian Genome Society

Jan 2, 2015

Darryl L HadsellTimothy C Cox

PMID: 25552398

DOI: 10.1007/s00335-014-9551-x

Abstract

Genetic background plays a dominant role in mammary gland development and breast cancer (BrCa). Despite this, the role of genetics is only partially understood. This study used strain-dependent variation in an inbred mouse mapping panel, to identify quantitative trait loci (QTL) underly...read more

Mentioned in this Paper

Conserved Synteny
Genome-Wide Association Study
In Silico
Quantitative Trait Loci
TBX3 gene
Mammary Tumorigenesis
Genome
Mammary Gland
Mammary Gland Development
Inbred Strain

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Breast Invasive Carcinoma (Keystone)

Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

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Invasive breast cancers indicate a spread into breast tissues and lymph nodes. Here are the latest discoveries pertaining to breast invasive carcinomas.

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