In situ and ex vivo evaluation of an arthroscopic indentation instrument to estimate the health status of articular cartilage in the equine metacarpophalangeal joint

Veterinary Surgery : VS
Harold BrommerJukka S Jurvelin

Abstract

To evaluate an arthroscopic indentation instrument (Artscan 200) for assessment of the health status of equine articular cartilage. In vitro experiment using equine isolated proximal phalanx (P1) specimens. P1 specimens from 39 horses (aged 1.5-22 years). Reproducibility was tested by determination of the coefficient of variation (CV). Dynamic modulus and cartilage degeneration index (CDI) values were measured at 2 predefined sites (site 1, joint margin; site 2, joint center) to assess the accuracy and to evaluate the relation with surface integrity. CV was 9.0%. A significant decrease in indenter force was identified when dynamic modulus values decreased to <2.5 MPa (range of tested samples 0.9-8.1 MPa) and when CDI values at site 1 increased to >50% (range 5.4-72.8%). Technique reproducibility was adequate but accuracy was limited. The device identified degeneration-associated decreases in cartilage stiffness only when the mechanical properties of the cartilage were considerably changed. Usefulness of this indentation instrument during arthroscopic surgery would be limited in the initial phase of OA-like cartilage degeneration, but may yield important information in more advanced OA.

References

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Citations

Aug 8, 2008·Knee Surgery, Sports Traumatology, Arthroscopy : Official Journal of the ESSKA·Hiroshi KurokiTakashi Nakamura
Nov 26, 2010·Journal of Medical Engineering & Technology·M A TimonenJ S Jurvelin
Jan 29, 2016·Annals of Biomedical Engineering·Joseph M MansourJean F Welter
Jun 25, 2013·Journal of Biomechanics·Grant M TarsiJonathan T Butcher
Oct 17, 2014·Annals of Biomedical Engineering·Jordan E TrachtenbergAntonios G Mikos
Nov 4, 2016·Annals of Biomedical Engineering·Jaakko K SarinIsaac O Afara
Jan 21, 2019·Osteoarthritis and Cartilage·F MaierD M Pierce

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