In situ antimicrobial behavior of materials with copper-based additives in a hospital environment

International Journal of Antimicrobial Agents
Humberto PalzaKatherine Delgado

Abstract

Copper and its alloys are effective antimicrobial surface materials in the laboratory and in clinical trials. Copper has been used in the healthcare setting to reduce environmental contamination, and thus prevent healthcare-associated infections, complementing traditional protocols. The addition of copper nanoparticles to polymer/plastic matrices can also produce antimicrobial materials, as confirmed under laboratory conditions. However, there is a lack of studies validating the antimicrobial effects of these nanocomposite materials in clinical trials. To satisfy this issue, plastic waiting room chairs with embedded metal copper nanoparticles, and metal hospital IV pools coated with an organic paint with nanostructured zeolite/copper particles were produced and tested in a hospital environment. These prototypes were sampled once weekly for 10 weeks and the viable microorganisms were analysed and compared with the copper-free materials. In the waiting rooms, chairs with copper reduced by around 73% the total viable microorganisms present, showing activity regardless of the microorganism tested. Although there were only low levels of microorganisms in the IV pools installed in operating rooms because of rigorous hygiene protocols...Continue Reading

Citations

Apr 22, 2020·Expert Review of Medical Devices·Jorge M Zuniga, Aaron Cortes
Oct 15, 2019·Environmental Toxicology and Chemistry·Zuzanna Gajda-MeissnerTeresa F Fernandes
Nov 18, 2018·Metallomics : Integrated Biometal Science·Emma TarrantKevin J Waldron
Apr 25, 2020·Nanomaterials·Maria Chiara SportelliNicola Cioffi
Jan 31, 2020·Neurochemical Research·Arundhati JoshiRalf Dringen
Nov 16, 2020·International Journal of Biological Macromolecules·Xia-Xiao WuGang-Biao Jiang
Feb 3, 2021·Membranes·Andreina GarcíaHumberto Estay
Oct 15, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Camilo Zamora-LedezmaFrank Alexis
Feb 23, 2021·Bioactive Materials·Erlin ZhangGaowu Qin
Aug 31, 2021·RSC Chemical Biology·Przemysław BiegańskiKonrad Kowalski
Sep 22, 2021·Microbial Drug Resistance : MDR : Mechanisms, Epidemiology, and Disease·Zamile N MbheleLinda A Bester
Oct 27, 2021·Critical Reviews in Microbiology·Wolfgang BäumlerWulf Schneider-Brachert

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