In Situ Formation of Nanofibers from Purpurin18-Peptide Conjugates and the Assembly Induced Retention Effect in Tumor Sites

Advanced Materials
Di ZhangHao Wang

Abstract

An assembly-induced retention effect for enhanced tumor photoacoustic (PA) imaging and therapeutics is described. A responsive small-molecule precursor is prepared that simultaneously self-assembles into nanofibers in tumor sites that exhibit an assembly-induced retention effect, which results in an improved PA imaging signal and enhanced therapeutic efficacy. This successful proof-of-concept study paves the way to develop novel supramolecular biomaterials for cancer diagnostics and therapeutics.

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Citations

Jul 3, 2016·Advanced Drug Delivery Reviews·Yin WangHonggang Cui
Jul 20, 2016·ACS Applied Materials & Interfaces·Hong-Wei AnHao Wang
Aug 17, 2016·ACS Applied Materials & Interfaces·Wei-Jiao LiuHao Wang
Feb 15, 2017·Advanced Materials·Pei-Pei YangHao Wang
Mar 25, 2017·Journal of Drug Targeting·Yujie JiZhipeng Chen
Feb 25, 2017·Advanced Materials·Qihang SunYouqing Shen
Jul 6, 2017·Small·Yao-Xin LinHao Wang
May 3, 2016·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Dan YuanBing Xu
Oct 19, 2016·Chemical Communications : Chem Comm·Wei JiChuanliang Feng
Oct 7, 2016·Chemical Society Reviews·Yizhong ShenHong-Yuan Chen
Mar 3, 2018·Chemical Society Reviews·Pengcheng ZhangHonggang Cui
Feb 21, 2018·Advanced Materials·Guo-Bin QiHao Wang
May 17, 2018·Chemistry : a European Journal·Ruibing AnHong Liu
Aug 8, 2017·Advanced Materials·Guo-Bin QiHao Wang
Aug 7, 2018·Advanced Healthcare Materials·Lingyun ZhouShu Wang
Aug 24, 2018·Advanced Healthcare Materials·Kuo ZhangHao Wang
Sep 28, 2018·Chemical Society Reviews·Yijing LiuXiaoyuan Chen
Dec 1, 2018·Nanoscale·Jing-Jing HuXian-Zheng Zhang
Apr 25, 2019·Advanced Materials·Jie GaoZhimou Yang
Sep 22, 2017·Current Medicinal Chemistry·Zhentao HuangYuan Gao
Jan 14, 2016·Nanoscale·Lei WangHao Wang
Oct 13, 2017·Current Medicinal Chemistry·Anutthaman ParthasarathyKarunakaran A Kalesh
Nov 22, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhen LeiZhenxin Wang
Oct 4, 2019·Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology·Xu Zhen, Xiqun Jiang

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