In situ synthesis of luminescent carbon nanoparticles toward target bioimaging

Nanoscale
Shazid Md SharkerSung Young Park

Abstract

This paper describes the in situ synthesis of single fluorescence carbon nanoparticles (FCNs) for target bioimaging applications derived from biocompatible hyaluronic acid (HA) without using common conjugation processes. FCNs formed via the dehydration of hyaluronic acid, which were obtained by carbonizing HA, and partially carbonized HA fluorescence carbon nanoparticles (HA-FCNs), formed by a lower degree of carbonization, show good aqueous solubility, small particle size (<20 nm) and different fluorescence intensities with a red shift. After confirming the cytotoxicity of HA-FCNs and FCNs, we carried out in vitro and in vivo bioimaging studies where HA-FCNs themselves functioned as single particle triggers in target imaging. The converted nanocrystal carbon particles from HA provide outstanding features for in vitro and in vivo new targeted delivery and diagnostic tools.

References

Dec 3, 2002·Nature Biotechnology·Jyoti K JaiswalSanford M Simon
Mar 5, 2003·Journal of Pharmaceutical and Biomedical Analysis·Jamal Alyoussef AlkradReinhard Neubert
Jul 2, 2004·Nature Reviews. Cancer·Bryan P Toole
Oct 16, 2004·Journal of Biomedical Materials Research. Part B, Applied Biomaterials·Kahp Y SuhRobert Langer
Jan 18, 2005·Journal of Controlled Release : Official Journal of the Controlled Release Society·W M TianH D Li
Mar 23, 2005·Carbohydrate Research·Mary K Cowman, Shiro Matsuoka
Aug 30, 2005·Toxicology in Vitro : an International Journal Published in Association with BIBRA·S M HussainJ J Schlager
Jul 25, 2007·Angewandte Chemie·Haipeng LiuChengde Mao
Sep 25, 2007·Nature Biotechnology·Hak Soo ChoiJohn V Frangioni
Dec 20, 2008·Nature Materials·Samir Mitragotri, Joerg Lahann
Mar 11, 2010·Advanced Materials·Goki EdaManish Chhowalla
May 5, 2010·International Journal of Pharmaceutics·Gurusamy SaravanakumarKinam Park
Aug 6, 2010·Angewandte Chemie·Sheila N Baker, Gary A Baker
Sep 24, 2010·ACS Nano·Matthew D MassichChad A Mirkin
Mar 3, 2011·Advanced Materials·Nishit DoshiSamir Mitragotri
Mar 19, 2011·Chemical Communications : Chem Comm·Zixue SuYang Zhang
May 10, 2012·Journal of Controlled Release : Official Journal of the Controlled Release Society·Emily Gullotti, Yoon Yeo
Jun 16, 2012·International Journal of Nanomedicine·Jonathan A CoulterKevin M Prise
Oct 23, 2012·Analytica Chimica Acta·Maria J Ruedas-RamaElizabeth A H Hall
Aug 30, 2013·Nature Communications·Yoshitake TodaHideo Hosono
Sep 7, 2013·Molecular Pharmaceutics· Abdullah-Al-NahainSung Young Park
Mar 7, 2014·Langmuir : the ACS Journal of Surfaces and Colloids·Xi ChenFrank Caruso
Aug 15, 2008·Food Chemistry·Jae Kyung KimJu Woon Lee
Jun 14, 2013·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zhu Lian WuCheng Zhi Huang
Nov 21, 2014·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Liang YangHyo-Kyung Han

❮ Previous
Next ❯

Citations

Sep 19, 2015·Journal of Controlled Release : Official Journal of the Controlled Release Society·Shazid Md SharkerSung Young Park
Oct 24, 2015·Luminescence : the Journal of Biological and Chemical Luminescence·Chan Jin JeongSung Young Park
Jun 24, 2015·ACS Applied Materials & Interfaces·Sung Han KimSung Young Park
Jan 8, 2020·The Analyst·Yihan WangXuemei Wang
Feb 28, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zihnil Adha Islamy MazradSung Young Park
Sep 14, 2017·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Zihnil Adha Islamy MazradSung Young Park
Nov 7, 2018·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Lizhen ZhangXing-Can Shen
Jul 19, 2017·Luminescence : the Journal of Biological and Chemical Luminescence·Zihnil Adha Islamy MazradSung Young Park
Jul 30, 2016·Biomaterials·Lingmin ZhangXingyu Jiang
Sep 7, 2017·ACS Applied Materials & Interfaces·Zihnil Adha Islamy MazradSung Young Park

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.