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In-solution Y-chromosome capture-enrichment on ancient DNA libraries

BMC Genomics

Aug 14, 2018

Diana I Cruz-DávalosMaria C. Avila-Arcos

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Abstract

As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach-in-solution capture-enrichment-retrieves sequences of interest and reduces the fraction of microbial DNA. In this work, we im...read more

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  • In-solution Y-chromosome capture-enrichment on ancient DNA libraries

    BMC Genomics

    Aug 14, 2018

    Diana I Cruz-DávalosMaria C. Avila-Arcos

    PMID: 30107783

    DOI: 10.1186/s12864-018-4945-x

    Abstract

    As most ancient biological samples have low levels of endogenous DNA, it is advantageous to enrich for specific genomic regions prior to sequencing. One approach-in-solution capture-enrichment-retrieves sequences of interest and reduces the fraction of microbial DNA. In this work, we im...read more

    37
    37

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