In-stent area stenosis on 64-slice multi-detector computed tomography coronary angiography: optimal cutoff value for minimum lumen cross-sectional area of coronary stents compared with intravascular ultrasound.

The International Journal of Cardiovascular Imaging
Woocheol KwonSung Gyun Ahn

Abstract

We aimed to prospectively assess the optimal cutoff value for a minimum lumen cross-sectional area (CSA) on a 64-slice multidetector computed tomography (MDCT) compared with an intravascular ultrasound (IVUS). In 39 patients with 43 stents, the minimum lumen diameter, stent diameter, diameter stenosis, minimum lumen CSA, stent CSA, and area stenosis at the narrowest point were measured independently on 64-slice MDCT and IVUS images. For the assessment of diameter and CSA, 64-slice MDCT showed good correlations with IVUS (r = 0.82 for minimum lumen diameter, r = 0.66 for stent diameter, r = 0.79 for minimum lumen CSA, and r = 0.75 for stent CSA, respectively, P < 0.0001). For the assessment of diameter and area stenoses, a 64-slice MDCT showed good correlations with IVUS (r = 0.89 and 0.91, respectively, P < 0.0001). The overall sensitivity, specificity, positive predictive value, and negative predictive value to detect in-stent area restenosis (≥ 50 % area stenosis) of a 64-slice MDCT were 77, 100, 100, and 91 %, respectively. The cutoff value of a 64-slice MDCT, determined by receiver operator characteristic (ROC) analysis, was 5.0 mm(2) with 76.5 % sensitivity and 92.3 % specificity for significant in-stent area restenosis; t...Continue Reading

References

Jul 16, 2005·International Journal of Cardiology·Toshiro KitagawaYoshitaka Sekiguchi
Aug 16, 2005·The American Journal of Cardiology·Christophe CaussinJean-François Paul
Jun 5, 2007·Journal of the American College of Cardiology·Filippo CademartiriJeroen J Bax
Dec 24, 2009·AJR. American Journal of Roentgenology·Joanna J WykrzykowskaMelvin E Clouse
Apr 10, 2010·Journal of Nuclear Cardiology : Official Publication of the American Society of Nuclear Cardiology·Nazario CarrabbaJeroen J Bax

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