In the shadow of the wrinkle: theories

Journal of Cosmetic Dermatology
Philippe HumbertPatrice Muret

Abstract

As time passes, wrinkles typically appear. These skin depressions that become deeper and deeper draw more and more coarser lines on almost all the visible parts of aging individual's skin. They are indeed the most obvious and maybe disliked signs of skin aging, and thus, preventing and treating them are a major topic for dermo-cosmetic laboratories. However, the cause and occurrence mechanism of these simplistic looking lines are not yet fully understood. Wrinkling is thought to be a complex biophysical process resulting from repeated strains on a progressively, structurally and biochemistry altered aging skin with impaired mechanical properties. Focus is made on the specific histological features of the wrinkle compared to the surrounding aging skin. The numerous age-related changes in human skin that are supposed to be involved in wrinkling are briefly reviewed, and the current theories on wrinkle formation linked to these changes are also discussed.

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Citations

Sep 22, 2015·Therapeutic Delivery·Jessica A Scott, Ajay K Banga
Dec 20, 2013·Aesthetic Surgery Journal·Joel E PessaPhilipp E Scherer
Sep 4, 2012·Journal of Cosmetic Dermatology·Marios PanasDimitrios Vassilopoulos
Mar 2, 2018·Plastic Surgical Nursing : Official Journal of the American Society of Plastic and Reconstructive Surgical Nurses·Kim Renton, Kathy Young Keefe
May 9, 2019·Journal of Cosmetic and Laser Therapy : Official Publication of the European Society for Laser Dermatology·Antonino Araco

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