In-tube solid-phase microextraction coupled by in valve mode to capillary LC-DAD: Improving detectability to multiresidue organic pollutants analysis in several whole waters

Journal of Chromatography. a
P Campíns-FalcóY Moliner-Martínez

Abstract

A simple and fast capillary chromatographic method has been developed to identify and quantify organic pollutants at sub-ppb levels in real water samples. The major groups of pesticides (organic halogens, organic phosphorous, and organic nitrogen compounds), some hydrocarbons (polycyclic aromatic hydrocarbons), phthalates and some phenols such as phenol and bisphenol A (endocrine disruptors) were included in this study. The procedure was based on coupling, in-tube solid-phase microextraction (IT-SPME) by using a conventional GC capillary column (95% methyl-5% phenyl substituted backbone, 80cmx0.32mm i.d., 3microm film thickness) in the injection valve to capillary liquid chromatography with diode array detection. A comparative study between the IT-SPME manifold and a column-switching device using a C(18) column (35mmx0.5mm i.d., 5microm particle size) has been performed. The IT-SPME procedure was optimal, it allows reaching limits of detection (LODs) between 0.008 and 0.2microg/L. No matrix effect was found and recoveries between 70 and 116% were obtained. The precision of the method was good, and the achieved intra- and inter-day variation coefficients were between 2 and 30%. This procedure has been applied to the screening an...Continue Reading

References

Jul 25, 2003·Journal of Chromatography. a·Yoshihiro Saito, Kiyokatsu Jinno
Apr 8, 2006·Journal of Chromatographic Science·Guilherme M Titato, Fernando M Lanças
Mar 4, 2008·Analytical and Bioanalytical Chemistry·Kerstin Greulich, Lutz Alder

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Citations

Jan 23, 2016·Journal of Chromatography. a·R A González-FuenzalidaP Campíns-Falcó
Jan 9, 2016·Analytical Chemistry·Meng MeiDongxing Yuan
Dec 18, 2015·Analytical Chemistry·Rodrigo A González-FuenzalidaPilar Campíns-Falcó
Jan 17, 2016·Analytica Chimica Acta·M Fernández-AmadoD Prada-Rodríguez
Jul 7, 2012·Biomedical Chromatography : BMC·Khalil FarhadiAmir Abbas Matin
Oct 10, 2014·Journal of Separation Science·Carme Valls-CantenysVictòria Salvadó
Sep 22, 2012·Journal of Chromatography. a·M Muñoz-OrtuñoP Campíns-Falcó
Dec 3, 2013·Journal of Chromatography. a·M Muñoz-OrtuñoP Campíns-Falcó
Dec 29, 2016·Analytical and Bioanalytical Chemistry·Susana Pitarch-AndrésJosep Esteve-Romero
Oct 22, 2016·Analytical and Bioanalytical Chemistry·Qi DengRavi Gooneratne
May 30, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Henry Daniel Ponce-RodríguezPilar Campíns-Falcó
Mar 17, 2020·Analytical and Bioanalytical Chemistry·Nicole Jaffrezic-RenaultZhenzhong Guo
Dec 29, 2020·Journal of Chromatography. a·Hiroyuki Kataoka

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