PMID: 19927404Jan 1, 1985Paper

In vitro 5-phosphoribosyl 1-pyrophosphate-independent salvage biosynthesis of ribo- and deoxyriboadenine nucleotides in Bacillus cereus

Biochimica Et Biophysica Acta
P L IpataM G Tozzi

Abstract

The pools of free ribose 1-phosphate and deoxyribose 1-phosphate have been measured in Bacillus cereus. It is shown that crude extracts of the same organism can actively utilize the sugar phosphates to convert adenine to ATP and deoxyATP, via a 'salvage' pathway, involving adenine ribosylation (or deoxyribosylation), followed by multiple phosphorylation steps. The biosynthetic pathway operates even in the presence of excess P(i') thus showing that purine nucleoside phosphorylases may function in vivo, contrary to what is generally assumed, as anabolic rather than catabolic enzymes.

References

Oct 1, 1975·Journal of Bacteriology·J M Magill, C W Magill
Jan 1, 1979·Annual Review of Biochemistry·L Thelander, P Reichard
May 1, 1975·Archives of Biochemistry and Biophysics·J G Blank, P A Hoffee
Feb 1, 1975·Biochemical Pharmacology·F P MiechD G Senft
Apr 1, 1971·Journal of Bacteriology·J Hoffmeyer, J Neuhard
Jul 1, 1967·Analytical Biochemistry·P L Ipata
Jul 1, 1982·Analytical Biochemistry·M G TozziU Mura
Sep 1, 1984·Journal of Biochemical and Biophysical Methods·P L Ipata, M G Tozzi
Dec 1, 1984·Journal of Biochemical and Biophysical Methods·M G TozziP L Ipata
Nov 1, 1980·Archives of Biochemistry and Biophysics·M CamiciU Mura
Mar 15, 1981·Analytical Biochemistry·P L Ipata, M Camici

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Citations

Mar 1, 1993·Comparative Biochemistry and Physiology. B, Comparative Biochemistry·H Trembacz, M M Jezewska
Dec 1, 1987·Archives of Biochemistry and Biophysics·U MuraP L Ipata
Mar 8, 2006·The FEBS Journal·Maria G TozziPiero L Ipata

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