In vitro Actinomyces israelii biofilm development on IUD copper surfaces

Mónica CarrilloMargarita Stoytcheva


Female pelvic actinomycosis may involve fallopian tubes, ovaries, uterus and bladder. This condition is often associated with the use of intrauterine contraceptive devices (IUDs), vaginal pessaries and/or tampons. The predominant causative agent of human actinomycosis is Actinomyces israelii, which has been found on copper IUDs retrieved from patients. In this work, a biofilm of A. israelii was developed in vitro on copper surfaces immersed in a simulated uterine fluid under anaerobic conditions. The biofilm was characterized using scanning electron microscopy (SEM), energy dispersive X-ray and atomic force microscopy. The capacity of A. israelii to develop a biofilm over copper surfaces in synthetic media was demonstrated. SEM micrographies illustrate the exopolysaccharides production and bacterial distribution. A. israelii was able to attach and grow in synthetic intrauterine media and to present on the copper surface is likely due to the production of biofilm.


Jun 1, 1992·Fertility and Sterility·D A Eschenbach
Feb 1, 1989·Radiology·K F O'ConnorS I Schabel
Sep 1, 1966·American Journal of Obstetrics and Gynecology·D R MishellD L Moyer
Apr 11, 2001·Emerging Infectious Diseases·R M Donlan
Nov 10, 2005·Journal of Medical Microbiology·Z PálE Nagy
May 29, 2007·Contraception·Carolyn Westhoff
Apr 12, 2008·Contraception·Francieli ChassotMarcia E L Consolaro
Jul 3, 2010·Cancer Cytopathology·Edmund Cibas

❮ Previous
Next ❯


Sep 2, 2015·International Journal of Medical Microbiology : IJMM·Paul VielkindCatalina-Suzana Stingu
Apr 14, 2015·Future Microbiology·Lyudmila BoyanovaIvan Mitov
Mar 20, 2015·Clinical Microbiology Reviews·Eija Könönen, William G Wade
Mar 22, 2020·Journal of Clinical Medicine·Julie CarraraCharlotte Vaysse
Feb 25, 2017·Research in Microbiology·Liselotte HardyTania Crucitti

❮ Previous
Next ❯

Related Concepts

Related Feeds


Actinomycosis is a rare, chronic, and slowly progressive granulomatous disease caused by filamentous Gram positive anaerobic bacteria from the Actinomycetaceae family (genus Actinomyces). The disease is characterised by the formation of painful abscesses in the mouth, lungs,breast or gastrointestinal tract. Discover the latest research on actinomycosis here.

Biofilm & Infectious Disease

Biofilm formation is a key virulence factor for a wide range of microorganisms that cause chronic infections.Here is the latest research on biofilm and infectious diseases.

Bladder Carcinoma In Situ

Bladder Carcinoma In Situ is a superficial bladder cancer that occurs on the surface layer of the bladder. Discover the latest research on this precancerous condition in this feed.

Related Papers

The European Journal of Contraception & Reproductive Health Care : the Official Journal of the European Society of Contraception
I LeteJ L de Pablo
Fertility and Sterility
Samuel Marcus, Diana Marcus
European Journal of Obstetrics, Gynecology, and Reproductive Biology
D HamidJ Ritter
© 2021 Meta ULC. All rights reserved