In vitro activities of antibiotics and antimicrobial peptides against the plant pathogenic bacterium Xylella fastidiosa

Letters in Applied Microbiology
L V KuzinaD A Cooksey

Abstract

The objective of this study was to evaluate the effectiveness of antibiotics and antimicrobial peptides against 10 strains of Xylella fastidiosa. The minimal inhibitory concentration (MIC) of 12 antibiotics and 18 antimicrobial peptides were determined by agar dilution tests and growth inhibition assays. Antibiotics with the lowest MIC for X. fastidiosa strains were gentamicin, tetracycline, ampicillin, kanamycin, and novobiocin, chloramphenicol, and rifampin. Plate growth inhibition assays showed that four of the antimicrobial peptides (Magainin 2, Indolicidin, PGQ, and Dermaseptin) were toxic to all X. fastidiosa strains. All X. fastidiosa strains were sensitive to several groups of antibiotics, and minor differences in sensitivity to several antimicrobial peptides were observed among strains. This study shows that antibiotics and antimicrobial peptides have some activity against the pathogen, X. fastidiosa and may have application in protecting plants from developing Pierce's disease.

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Citations

Oct 9, 2009·Current Microbiology·Christina E MaddoxLi Tian
Jan 20, 2009·Applied and Environmental Microbiology·Ayumi MatsumotoMichele M Igo
Apr 29, 2008·Annual Review of Phytopathology·Jose F MarcosBelén López-García
Apr 17, 2015·BMC Research Notes·Kameka L JohnsonPatricia Mowery
Mar 21, 2007·FEMS Microbiology Letters·Emilio Montesinos
Oct 12, 2016·Genetics and Molecular Biology·João Lúcio AzevedoPaulo Teixeira Lacava
Sep 28, 2018·Frontiers in Microbiology·Ifigeneia KyrkouLars Hestbjerg Hansen
Nov 26, 2021·Frontiers in Microbiology·Luís MollAnna Bonaterra

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