In vitro activities of ciprofloxacin, cefotaxime, ceftriaxone, chloramphenicol, and rifampin against fully susceptible and moderately penicillin-resistant Neisseria meningitidis.

Antimicrobial Agents and Chemotherapy
J M Blondeau, Y Yaschuk

Abstract

Moderately penicillin-resistant Neisseria meningitidis was responsible for an outbreak of meningococcal disease in Saskatoon, Saskatchewan, Canada in 1993. We tested fully susceptible and moderately resistant strains of N. meningitidis against ciprofloxacin, cefotaxime, ceftriaxone, chloramphenicol, penicillin, and rifampin. Eighteen percent of the isolates were moderately resistant to penicillin (MIC > or = 0.06 microgram/ml) whereas susceptibility was 100% for the other agents tested.

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Citations

Jul 18, 2003·Current Infectious Disease Reports·Philippe Cottagnoud, Martin G. Täuber
Apr 30, 1999·International Journal of Antimicrobial Agents·J M BlondeauE Silveira
Jun 1, 1997·Infectious Disease Clinics of North America·S E Beekmann, B N Doebbeling
Feb 28, 2002·Clinical Microbiology and Infection : the Official Publication of the European Society of Clinical Microbiology and Infectious Diseases·Marleen Van LooverenHerman Goossens
Nov 9, 2000·Canadian Journal of Microbiology·J M Blondeau, D Vaughan

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