In vitro activities of Y-688, a new 7-substituted fluoroquinolone, against anaerobic bacteria.

Antimicrobial Agents and Chemotherapy
A P MacGowanD Reeves

Abstract

The in vitro activities of Y-688, a new 7-substituted fluoroquinolone derivative, against 317 nonduplicate anaerobic isolates were determined. Eighty-five percent of the Bacteroides fragilis group (n = 89) were inhibited by < or = 2 mg of Y-688 per liter, while 78, 100, 89, and 98% of gram-negative bacilli (n = 135), gram-positive cocci (n = 59), and non-spore-forming (n = 58) and spore-forming (n = 51) gram-positive bacilli, respectively, were inhibited by < or = 1 mg of Y-688 per liter.

References

May 1, 1991·Journal of Medical Microbiology·D A Murdoch, I J Mitchelmore
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Aug 1, 1993·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·C E NordI Persson
Aug 1, 1996·The Journal of Antimicrobial Chemotherapy·K E BowkerA P MacGowan

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