In vitro activity of eravacycline and comparator antimicrobials against 143 recent strains of Bacteroides and Parabacteroides species

Anaerobe
Ellie J C GoldsteinK L Tyrrell

Abstract

Eravacycline, a novel fluorocycline antibiotic, has been evaluated against complicated mixed aerobic/anaerobic intra-abdominal infections but scant supporting in vitro data against anaerobes has been published. We found that eravacycline had good anaerobic in vitro activity with MICs of 4 μg/ml or less against all Bacteroides and Parabacteroides strains tested, except for two B. ovatus strains that had MICs of 8 μg/ml and one strain that had an MIC of 16 μg/ml. Eravacycline was four-to-eight fold more active than tigecycline.

Citations

Jun 9, 2019·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·Young Ran Lee, Caitlin Elizabeth Burton
Oct 18, 2019·Expert Review of Anti-infective Therapy·Philippe MontraversAlexy Tran-Dinh
Jan 17, 2020·Pharmacotherapy·Sara AlosaimyMichael J Rybak
Sep 16, 2020·The Journal of Antimicrobial Chemotherapy·Anthony M BuckleyMark H Wilcox
Dec 12, 2020·Infectious Disease Clinics of North America·Dennis L StevensEllie Jc Goldstein
Jan 29, 2021·Journal of Global Antimicrobial Resistance·Sebastian Martin Michael RongCatalina-Suzana Stingu
Apr 25, 2021·Annals of Clinical Microbiology and Antimicrobials·Seyedesomaye JasemiMohammad Mehdi Feizabadi

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