In vitro activity of temocillin (BRL 17421), a novel beta-lactamase-stable penicillin.

Antimicrobial Agents and Chemotherapy
L Verbist

Abstract

The new in vitro activity of temocillin (BRL 17421), a new beta-lactamase-stable penicillin, was compared with those of other beta-lactam antibiotics for over 500 clinical bacterial isolates. Temocillin inhibited 94% of the Enterobacteriaceae organisms at concentrations of 0.5 to 8 microgram/ml, regardless of organisms resistance to ampicillin, ticarcillin, cefazolin, or combinations thereof. Most pseudomonas aeruginosa isolates and all staphylococci and streptococci tested were resistant to temocillin.

References

May 1, 1980·Antimicrobial Agents and Chemotherapy·L Verbist, J Verhaegen

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Citations

Feb 1, 1985·European Journal of Clinical Microbiology·P C FuchsR N Jones
Jan 1, 1984·Diagnostic Microbiology and Infectious Disease·P C FuchsC Thornsberry
Jan 1, 1984·Antimicrobial Agents and Chemotherapy·L Verbist, J Verhaegen
Sep 1, 1984·Antimicrobial Agents and Chemotherapy·M FuksaA Lee
Aug 19, 2008·Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society·Lisa KentJ Stuart Elborn
Oct 19, 2014·The Journal of Antimicrobial Chemotherapy·Stewart BarkerThomas J Smith
Aug 30, 2017·Clinical Pharmacokinetics·Kevin Alexandre, Bruno Fantin

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