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In vitro adsorption of diphenoxylate hydrochloride on activated charcoal and its relationship to pharmacological effects of drug in vivo. I

Journal of Pharmaceutical Sciences

Nov 1, 1975

D R Sanvordeker, E Z Dahani

PMID: 485

Abstract

The adsorption of diphenoxylate hydrochloride, a potent antidiarrheal agent, on activated charcoal powder was studied in vitro. Langmuir adsorption isotherms were established at pH 4 and 7, and the maximum adsorption capacity of charcoal for this drug was estimated using these values. A...read more

Mentioned in this Paper

Chromium
Activated charcoal powder
Diphenoxylate Hydrochloride
Gastrointestinal Transit Procedure
Adsorption
Charcoal
Oxides
Activated Charcoal
Chromium oxide
Intestinal Motility
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In vitro adsorption of diphenoxylate hydrochloride on activated charcoal and its relationship to pharmacological effects of drug in vivo. I

Journal of Pharmaceutical Sciences

Nov 1, 1975

D R Sanvordeker, E Z Dahani

PMID: 485

DOI:

Abstract

The adsorption of diphenoxylate hydrochloride, a potent antidiarrheal agent, on activated charcoal powder was studied in vitro. Langmuir adsorption isotherms were established at pH 4 and 7, and the maximum adsorption capacity of charcoal for this drug was estimated using these values. A...read more

Mentioned in this Paper

Chromium
Activated charcoal powder
Diphenoxylate Hydrochloride
Gastrointestinal Transit Procedure
Adsorption
Charcoal
Oxides
Activated Charcoal
Chromium oxide
Intestinal Motility

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