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In vitro adsorption of diphenoxylate hydrochloride on activated charcoal and its relationship to pharmacological effects of drug in vivo. I

Journal of Pharmaceutical Sciences

Nov 1, 1975

Dilip R Sanvordeker, E Z Dahani

PMID: 485

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Abstract

The adsorption of diphenoxylate hydrochloride, a potent antidiarrheal agent, on activated charcoal powder was studied in vitro. Langmuir adsorption isotherms were established at pH 4 and 7, and the maximum adsorption capacity of charcoal for this drug was estimated using these values. A...read more

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Diphenoxylate Hydrochloride
Intestinal Motility
Isonipecotic Acids
Chromium
Chromium oxide
Hydrogen-Ion Concentration
Actidose
In Vitro [Publication Type]
Adsorption
Diphenoxylate
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  • In vitro adsorption of diphenoxylate hydrochloride on activated charcoal and its relationship to pharmacological effects of drug in vivo. I

    Journal of Pharmaceutical Sciences

    Nov 1, 1975

    Dilip R Sanvordeker, E Z Dahani

    PMID: 485

    DOI:

    Abstract

    The adsorption of diphenoxylate hydrochloride, a potent antidiarrheal agent, on activated charcoal powder was studied in vitro. Langmuir adsorption isotherms were established at pH 4 and 7, and the maximum adsorption capacity of charcoal for this drug was estimated using these values. A...read more

    Mentioned in this Paper

    Diphenoxylate Hydrochloride
    Intestinal Motility
    Isonipecotic Acids
    Chromium
    Chromium oxide

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