In vitro adsorption of gentamicin and netilmicin by polyacrylonitrile and polyamide hemofiltration filters.

Antimicrobial Agents and Chemotherapy
Philip K N LamCharles D Gomersall

Abstract

Adsorption of gentamicin and netilmicin by new polyacrylonitrile and polyamide hemofiltration filters was studied over 4 h, using a single-compartment in vitro continuous venovenous hemofiltration model. After the first dose (16.6 mg of gentamicin, 19.3 mg of netilmicin), 14.9 mg of gentamicin and 19.2 mg of netilmicin were adsorbed to polyacrylonitrile filters in vitro. Adsorption by polyacrylonitrile filters was rapid and irreversible and could be increased by repeated dosing. Adsorption by polyamide filters was substantially less.

References

Feb 15, 1979·Klinische Wochenschrift·D Kraft, H Lode
Jan 1, 1991·Contributions to Nephrology·S Cigarran-GuldrisT A Golper
Dec 19, 2007·Antimicrobial Agents and Chemotherapy·Qi TianGordon Y S Choi

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Citations

Feb 24, 2015·Diagnostic Microbiology and Infectious Disease·Janattul-Ain JamalJason A Roberts
Oct 21, 2019·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Dariusz OnichimowskiMirosław Czuczwar
Nov 20, 2016·Critical Care : the Official Journal of the Critical Care Forum·Gianluca VillaChiara Adembri
Sep 10, 2015·The International Journal of Artificial Organs·Janattul-Ain JamalJason A Roberts
Jun 4, 2019·European Journal of Hospital Pharmacy. Science and Practice·Jesus RuizPaula Ramirez
Oct 10, 2020·Journal of Artificial Organs : the Official Journal of the Japanese Society for Artificial Organs·Dariusz OnichimowskiMirosław Czuczwar
Aug 6, 2021·The International Journal of Artificial Organs·Frédéric J BaudLionel Lamhaut

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