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In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Apr 30, 2009

Pina M CardarelliDavid J King

Abstract

This study was undertaken to evaluate the effects of MDX-1401, a nonfucosylated fully human monoclonal antibody that binds to human CD30, and to determine whether it exhibits greater in vitro and in vivo activity than its parental antibody. Assays measuring antibody binding to CD30-expr...read more

Mentioned in this Paper

Pathologic Cytolysis
Cricetulus
Monoclonal Antibodies
FCGR3B protein, human
Xenograft Model Antitumor Assays
Antigens, CD16
Binding Sites, Antibody
Chinese Hamster Ovary Cell
Antibody Avidity
Leu-11 Antigens
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In vitro and in vivo characterization of MDX-1401 for therapy of malignant lymphoma

Clinical Cancer Research : an Official Journal of the American Association for Cancer Research

Apr 30, 2009

Pina M CardarelliDavid J King

PMID: 19401346

DOI: 10.1158/1078-0432.ccr-08-3222

Abstract

This study was undertaken to evaluate the effects of MDX-1401, a nonfucosylated fully human monoclonal antibody that binds to human CD30, and to determine whether it exhibits greater in vitro and in vivo activity than its parental antibody. Assays measuring antibody binding to CD30-expr...read more

Mentioned in this Paper

Pathologic Cytolysis
Cricetulus
Monoclonal Antibodies
FCGR3B protein, human
Xenograft Model Antitumor Assays
Antigens, CD16
Binding Sites, Antibody
Chinese Hamster Ovary Cell
Antibody Avidity
Leu-11 Antigens

Related Papers

Paper Details
References
  • References
  • Citations12
  • finger pointing at paper

    References currently unavailable

    We're still populating references for this paper, please check back later.
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