In vitro and in vivo Nematocidal Activity of Allium sativum and Tagetes erecta Extracts Against Haemonchus contortus

Türkiye parazitolojii dergisi
Josefina Palacio- LandínMaría Guadalupe Valladares-Cisneros

Abstract

In the Mexican ethno-medicine, a number of plants have shown a successful anthelmintic activity. This fact could be crucial to identify possible green anti-parasitic strategies against nematodes affecting animal production. This research evaluated the in vitro and in vivo nematocidal effects of two single and combined plant extracts: bulbs of Allium sativum (n-hexane) and flowers of Tagetes erecta (acetone). The in vivo assay evaluated the administration of extracts either individually or combined against Haemonchus contortus in experimentally infected gerbils. The in vitro larvicidal activity percentage (LAP) of A. sativum and T. erecta extracts against H. contortus (L3) was determined by means of individual and combined usage of the extracts. Similarly, the extracts were evaluated in terms of reduction in the parasitic population in gerbils infected with H. contortus by individual and combined usage. The LAP at 40 mg/mL was 68% with A. sativum and 36.6% with T. erecta. The combination caused 83.3% mortality of parasites. The oral administration of A. sativum and T. erecta extracts at 40 mg/mL, caused 68.7% and 53.9% reduction of the parasitic burden, respectively. Meanwhile, the combined effect of both extracts shown 87.5% re...Continue Reading

Citations

Mar 14, 2017·Journal of Ethnopharmacology·Denia M Piña-VázquezFausto Arellano-Carbajal
Mar 13, 2018·Parasite : Journal De La Société Française De Parasitologie·Sujogya Kumar Panda, Walter Luyten
Feb 9, 2017·Journal of Helminthology·I Blasco-Costa, R Poulin
Jul 31, 2020·Journal of Medicinal Food·Manases González-CortázarLiliana Aguilar-Marcelino
May 26, 2017·Parasitology Research·Alba CortésCarla Muñoz-Antolí
Mar 7, 2019·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Beatriz Hernández-Carlos, Marcela Gamboa-Angulo

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Anthelmintics (ASM)

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

Anthelmintics

Anthelmintics or antihelminthics are a group of antiparasitic drugs that expel parasitic worms (helminths) and other internal parasites from the body by either stunning or killing them and without causing significant damage to the host. Discover the latest research on anthelmintics here.

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