In vitro antibacterial activity of seven Indian spices against high level gentamicin resistant strains of enterococci

Archives of Medical Science : AMS
Sharma RevatiBhattacharjee Minakshi

Abstract

The aim of the study was to explore the in vitro antibacterial activity of seven ethanolic extracts of spices against high level gentamicin resistant (HLGR) enterococci isolated from human clinical samples. Two hundred and fifteen enterococcal strains were isolated from clinical samples. High level gentamicin resistance in ethanolic extracts of cumin (Cuminum cyminum), cinnamon (Cinnamomum zeylanicum), ginger (Zingiber officinale), fenugreek (Trigonella foenum-graecum), cloves (Syzygium aromaticum), cardamom (Elettaria cardamomum Maton) and black pepper (Piper nigrum) were prepared using Soxhlet apparatus. The antibacterial effect of the extracts was studied using the well diffusion method. Statistical analysis was carried out by χ(2) test using SPSS 17 software. Only cinnamon and ginger were found to have activity against all the isolates, whereas cumin and cloves had a variable effect on the strains. Fenugreek, black pepper and cardamom did not show any effect on the isolates. The zone diameter of inhibition obtained for cinnamon, ginger, cloves and cumin was in the range 31-34 mm, 27-30 mm, 25-26 mm and 19-20 mm respectively. Cinnamomum zeylanicum and Z. officinale showed the maximum antibacterial activity against the entero...Continue Reading

Citations

Mar 28, 2017·Critical Reviews in Microbiology·Anna MarcheseMarjan Ajami
Jun 18, 2017·International Journal of Molecular Sciences·Qing LiuHua-Bin Li

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BETA
motility test

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