In vitro antibiotic susceptibility of field isolates of Mycoplasma synoviae in Argentina

Avian Diseases
R O CerdáM F Landoni

Abstract

Minimum inhibitory concentrations (MICs) were determined in vitro for 7 antibiotics (aivlosin, enrofloxacine, tylosin, tiamulin, kitasamycin, chlortetracycline, and oxytetracycline) against eight recent local Argentinean isolates and two standard strains of Mycoplasma synoviae. Aivlosin (3-acetyl-4"-isovaleryl tylosin tartrate), tylosin, and tiamulin showed the lowest MICs with MIC90s of 0.006, 0.012, and 0.05 microg/ml, respectively. Except one strain that showed resistant values to chlortetracycline (> or = 12.5 microg/ml), all the analyzed strains were susceptible in different degrees to all the antibiotics tested. In this study, the improved activity of the tylosin-derived drug, aivlosin, was confirmed because it showed, in most strains, MIC values half those for tylosin.

Citations

Feb 7, 2008·Avian Diseases·Meghan MayDaniel R Brown
Apr 25, 2013·Antimicrobial Agents and Chemotherapy·I LysnyanskyS Levisohn
May 7, 2010·Journal of Veterinary Pharmacology and Therapeutics·R O CerdáM Landoni
May 19, 2012·Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association·Arturo AnadónMaría Rosa Martínez-Larrañaga
Nov 19, 2017·BMC Veterinary Research·Zsuzsa KreizingerMiklós Gyuranecz
Jul 14, 2018·Microbiology Spectrum·Anne V Gautier-Bouchardon

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