In vitro antimicrobial activity of root canal sealers and calcium hydroxide paste

Contemporary Clinical Dentistry
Alessandro L CavalcantiRicardo D Castro


To evaluate the in vitro antimicrobial activity of different root canal sealers and calcium hydroxide (CH) paste. The sample was composed of two sealers (Fill Canal(®) and Sealer 26(®)), one CH cement (Hydro C(®)), and a CH paste. The agar diffusion test was performed in Petri dishes inoculated with the following microorganisms: Streptococcus salivarius, Streptococcus oralis, Streptococcus mitis, Lactobacillus casei, Streptococcus mutans, Candida albicans, Candida krusei, and Candida tropicalis. The diameters of the zones of microbial growth inhibition were measured after 24 h. The tests were performed in triplicate. Data were analyzed statistically by ANOVA and Tukey's test at 5% significance level. Fill Canal(®) exhibited the largest mean zone of microbial growth inhibition against the Candida species and differed significantly from the other groups (P < 0.001). When inhibition was observed against S. mitis and S. oralis, the CH paste presented a larger mean zone of microbial growth inhibition than those of the other materials (P < 0.05). Regarding the inhibition of S. mutans, a statistically significant difference was observed only between the CH paste and Hydro C(®) (P < 0.05); the paste produced the largest mean zone of mi...Continue Reading


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Related Concepts

Calcium hydroxide
Candida (fungus)
Candida albicans
Laboratory Procedures
Lactobacillus casei
Streptococcus mutans
Pulp Canals
Streptococcus oralis
Streptococcus salivarius

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