PMID: 2098705Oct 1, 1990Paper

In vitro antimicrobial sensitivity of enteric rods and pseudomonads from advanced adult periodontitis

Oral Microbiology and Immunology
J SlotsT E Rams

Abstract

The prevalence and in vitro antimicrobial sensitivity of isolates of enteric rods and pseudomonads was examined in 844 adult periodontitis patients. These organisms were recovered from 13.5% of the study subjects. Ciprofloxacin exhibited the highest inhibitory activity of the 14 oral antimicrobial agents tested. Beta-lactam antibiotics were largely ineffective, and tetracycline failed to inhibit most Pseudomonas species. In vitro sensitivity data suggest that a subgingival microbiota comprising mainly streptococci would result from therapy that combined ciprofloxacin and metronidazole. Since streptococci may inhibit the growth of several putative periodontal pathogens, populations of "beneficial" streptococci in the periodontal pocket might constitute a very attractive therapeutic outcome. Controlled clinical studies are needed to clarify the possible role of ciprofloxacin in the treatment of destructive periodontitis.

References

Oct 1, 1979·Journal of Clinical Periodontology·J Slots
Aug 1, 1990·Journal of Clinical Periodontology·J Slots, T E Rams
Oct 1, 1989·Clinical Microbiology Reviews·J S Wolfson, D C Hooper
Jan 1, 1986·Antimicrobial Agents and Chemotherapy·T A TartaglioneT M Kerkering
May 1, 1988·Journal of Periodontal Research·Y MiyakeH Suginaka
Jul 1, 1988·Journal of Clinical Periodontology·A D HaffajeeJ L Ebersole
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May 1, 1988·Journal of Clinical Periodontology·J L DzinkA D Haffajee
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Apr 1, 1982·Journal of Clinical Microbiology·J Slots

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Citations

Apr 14, 1999·Periodontology 2000·C ScullyM R Sposto
Oct 7, 2000·Journal of Periodontology·T B ConwayJ D Walters
Sep 1, 1991·Journal of Periodontology·J SlotsG M Gillespie
May 16, 2002·Periodontology 2000·Jørgen Slots, Miriam Ting
Aug 28, 2004·Periodontology 2000·Makoto UmedaIsao Ishikawa
Nov 1, 2004·Journal of Periodontology
Mar 1, 1994·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·C M Sedgley, L P Samaranayake
May 13, 1999·Periodontology 2000·J SlotsH Nowzari
May 23, 2002·Antimicrobial Agents and Chemotherapy·David A Cacchillo, John D Walters
Aug 7, 2007·Expert Review of Anti-infective Therapy·Hans-Peter Horz, Georg Conrads
Dec 18, 2007·Journal of Clinical Periodontology·David HerreraRubén León
Oct 1, 2007·Journal of Applied Oral Science : Revista FOB·Cláudia de Moura CarreiraJosé Luiz Lage-Marques
Nov 1, 1996·Annals of Periodontology·G C Armitage
Oct 1, 1993·Oral Microbiology and Immunology·M J Flynn, J Slots
Nov 1, 1996·Annals of Periodontology·C H Drisko
Feb 1, 1996·Periodontology 2000·A J van WinkelhoffJ Slots
Feb 6, 2004·Pesquisa odontológica brasileira = Brazilian oral research·Cláudio Mendes PannutiDanilo Falsi
Nov 5, 2005·Journal of Clinical Periodontology·Adriana JaramilloAdolfo Contreras
Aug 23, 2012·Periodontology 2000·Jørgen Slots
Aug 1, 1993·Journal of Periodontology·Jeffrey M Gordon, Clay B Walker
Mar 21, 2019·Periodontology 2000·Jørgen Slots
Dec 1, 1990·Oral Microbiology and Immunology·J SlotsT E Rams
Oct 1, 1993·Scandinavian Journal of Dental Research·R PajukantaH Jousimies-Somer
Aug 28, 2004·Periodontology 2000·Clay B WalkerPierre Baehni
Jan 7, 2005·Journal of Periodontology·Jørgen Slots, UNKNOWN Research, Science and Therapy Committee
Jan 14, 2005·The Journal of the American Dental Association·Tolga F TözümAtilla Bozkurt

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