In vitro assessment of interaction between lidocaine hydrochloride and sodium hypochlorite on root canal dentin before and after chemomechanical instrumentation procedures

Journal of Conservative Dentistry : JCD
Balasubramanian SaravanakarthikeyanSekar Mahalaxmi

Abstract

To investigate the effect of resultant precipitate formed on interaction between 2% lidocaine hydrochloride with adrenaline (LA) and 2.5% sodium hypochlorite (NaOCl) on root canal dentin before and after chemomechanical preparation, using scanning electron microscopy (SEM). Sixty mandibular premolars were decoronated, and the root length was standardized. All specimens were randomly distributed into the following three groups: Group I (control): 2% LA mixed with sterile water without root canal instrumentation, Group II: 2% LA with 2.5% NaOCl and no instrumentation, and Group III: 2% LA with 2.5% NaOCl, followed by mechanical instrumentation with rotary files. Teeth samples were sectioned into three parts, split and SEM analysis of the root canal wall was done at cervical, middle, and apical root thirds. SEM images revealed patent dentinal tubules with no precipitate occlusion in the control group, whereas there was occlusion of dentinal tubules with a precipitate in all the specimens in Group II and Group III at all the three root levels studied. The precipitate formed on the interaction between 2% LA solution and 2.5% NaOCl tends to occlude the dentinal tubules at the coronal, middle, and apical root thirds. The chemomechanic...Continue Reading

References

Jan 1, 1975·Journal of Endodontics·J Birchfield, P A Rosenberg
May 1, 1992·The Journal of the American Dental Association·R E Walton, M Torabinejad
Aug 1, 1990·Endodontics & Dental Traumatology·D Orstavik, M Haapasalo
Feb 1, 1990·Journal of Endodontics·M R ByersC L Kimberly
Sep 1, 1994·Oral Surgery, Oral Medicine, and Oral Pathology·R Garberoglio, C Becce
May 29, 2000·Endodontics & Dental Traumatology·I Potocnik, F Bajrović
May 7, 2005·International Endodontic Journal·C S TeixeiraW T Felippe
Apr 25, 2006·Journal of Endodontics·Matthias Zehnder
Sep 20, 2007·Journal of Endodontics·Bettina R BasraniAldo Manzur
Nov 26, 2008·Journal of Endodontics·Brian J RasimickAllan S Deutsch
Jan 27, 2009·Journal of Endodontics·Isabel Peixoto TortamanoPaschoal Laércio Armonia
Mar 27, 2009·European Journal of Oral Sciences·Floor M D OosterinkJohan Hoogstraten
Aug 16, 2013·Journal of Pharmacy & Bioallied Sciences·Thangavel BoopathiAruna Raj
Feb 3, 2016·Journal of Endodontics·Ekim Onur OrhanBekir Karabucak

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Methods Mentioned

BETA
nuclear magnetic resonance
NMR

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