In vitro assessment of the antifungal effects of neem powder added to polymethyl methacrylate denture base material

Journal of Clinical and Experimental Dentistry
Shorouq-Khalid HamidMohammed-Moustafa Gad

Abstract

Denture with antimicrobial activities is desirable to prevent Candida albican adhesion subsequently decreasing the susceptibility of denture stomatitis incidence. Azadirachta Indica, commonly known as Neem powder has antimicrobial effect but the effect of its addition to acrylic denture base on C. albicans adhesion has not been investigated. The aim of this study was determine whether adding neem powder to acrylic denture base materials could reduce Candida albicansadhesion. One hundred and twenty acrylic resin denture specimens were fabricated and divided into heat-polymerized (n=60) and auto-polymerized (n=60) groups. Each group was further divided into 6 groups (n=10) based on the neem concentration: 0, 0.5, 1, 1.5, 2 and 2.5 wt% of the polymer. After polymerization, the specimens were polished, stored in distilled water, sonicated, sterilized, submerged in artificial saliva containing C. albicans, and finally, placed in an incubator at 37°C. Slide counting and direct culture methods were used to assess the antifungal effects of the neem addition. An analysis of variance and post hoc Tukey's test were performed for the data analysis (p≤0.05 was statistically significant). Based on the results, the neem addition significantly...Continue Reading

Citations

Oct 28, 2019·Journal of Prosthodontics : Official Journal of the American College of Prosthodontists·Mohammed Ali AlBin-AmeerMohammed M Gad
Dec 17, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Katarzyna WalczakMieszko Wieckiewicz
Aug 18, 2020·The Journal of Prosthetic Dentistry·Steve AnRobert M Love

❮ Previous
Next ❯

Methods Mentioned

BETA
scraping

Software Mentioned

SPSS Statistics

Related Concepts

Related Feeds

Candida albicans

Candida albicans is an opportunistic, fungal pathogen of humans that frequently causes superficial infections of oral and vaginal mucosal surfaces of debilitated and susceptible individuals. Discover the latest research on Candida albicans here.

Candidiasis

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.

Candidiasis (ASM)

Candidiasis is a common fungal infection caused by Candida and it can affect many parts for the body including mucosal membranes as well as the gastrointestinal, urinary, and respiratory tracts. Here is the latest research.