In vitro atrial flow dynamics: normal conditions versus atrial fibrillation

Journal of Biomechanics
F MouretR Rieu

Abstract

The flow dynamics in the atrium is poorly described. The reasons are principally due to the complicated geometry of the cavity and its contractility. The present in vitro study focuses on the description of the flow in the left atrium in normal conditions (NC) and in atrial fibrillation (AF). The final objective is to give leads to understand, from the hemodynamic point of view, complications in case of AF. An atrio-ventricular dual activation system is used to simulate physiological flow in the left atrium. The cavities are compliant and transparent. Velocity measurements are performed with Particle Image Velocimetry. Systolic peak of the pulmonary venous flow is about 0.4 m s(-1) and diastolic peak 0.6 m s(-1) in magnitude. Vortices appear during diastasis and systole and are of normal size and duration. In early and late diastole, the ventricular filling (in NC and AF) and the atrial contraction (in NC only) create a characteristic flow pattern that consists in directed flow towards the mitral valve. In AF an increased resident time (500 ms versus 300 ms) and a slow helical flow pattern (about 0.1 m s(-1)), similar to what is measured using ultrasound echocardiography are observed. This study uses atrial flow dynamics descri...Continue Reading

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Citations

Dec 31, 2014·Journal of Biomechanics·Ryo KoizumiTomoyuki Yambe
Mar 31, 2016·Journal of Cardiovascular Electrophysiology·Felipe BisbalLluís Mont
May 24, 2013·Journal of Biomechanical Engineering·Ettore Lanzarone, Fabrizio Ruggeri
Jun 30, 2016·Innovations : Technology and Techniques in Cardiothoracic and Vascular Surgery·Pieter W J LozekootSandro Gelsomino
Jan 9, 2019·Frontiers in Physiology·Desmond Dillon-MurphyAdelaide de Vecchi
May 15, 2010·ASAIO Journal : a Peer-reviewed Journal of the American Society for Artificial Internal Organs·Riccardo VismaraCarlo Antona

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