PMID: 7013400Jul 1, 1980Paper

In vitro conversion of proinsulin to insulin by cathepsin B in isolated islets and its inhibition by cathepsin B antibodies

Acta diabetologica latina
R BansalJ R Kidwai

Abstract

Purified bovine cathepsin B, when incubated with isolated rat islets of Langerhans, completely converts proinsulin to insulin as demonstrated by the incorporation of 14C-leucine into islet proteins, releasing lysine as the only basic amino acid. Cathepsin B antibodies raised in rabbit inhibited the above conversion.

References

Sep 1, 1978·Journal of Biochemistry·T TowatariN Katunuma
Sep 1, 1978·Acta diabetologica latina·R B PuriV K Mohan Rao
Apr 1, 1973·The Biochemical Journal·A J Barrett
Feb 1, 1974·The Biochemical Journal·M C BurleighG S Lazarus
Nov 25, 1974·Biochimica Et Biophysica Acta·W HuismanM Gruber
Nov 25, 1974·Biochimica Et Biophysica Acta·V NinjoorA L Tappel
Jul 25, 1971·Biochimica Et Biophysica Acta·W Goettlich-RiemannA L Tappel
Sep 20, 1938·The Journal of General Physiology·M L Anson

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Citations

Dec 1, 1993·International Journal for Parasitology·A M SmithJ P Dalton
Nov 1, 1993·Molecular and Biochemical Parasitology·A M SmithJ P Dalton
Jan 1, 1982·Clinical and Experimental Hypertension. Part A, Theory and Practice·J A LuetscherG Grislis
Jan 1, 1983·European Journal of Cancer & Clinical Oncology·K PavelićS Vuk-Pavlović
Jan 1, 1984·Journal of Cellular Biochemistry·D F SteinerR Carroll
Mar 29, 1983·Biochemical and Biophysical Research Communications·B BeckG Debry

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