In vitro culture under physiologic oxygen concentration improves blastocyst yield and quality: a prospective randomized survey on sibling oocytes

Fertility and Sterility
H Nadir CirayMustafa Bahceci

Abstract

A prospective randomized study was carried on sibling oocytes in which human gametes and embryos were cultured at physiologic (6% CO(2) + 5% O(2) + 89% N(2)) condition from insemination to day 6 or at atmospheric (6% CO(2) in air) condition until day 3 and at physiologic environment afterward. The results showed that physiologic oxygen concentration throughout culture period improved total blastocyst yield and day 5 embryo quality.

Associated Clinical Trials

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Citations

Jun 21, 2012·Journal of Assisted Reproduction and Genetics·Haydar Nadir CirayMustafa Bahceci
Jul 10, 2013·Journal of Assisted Reproduction and Genetics·Esti KastersteinRaphael Ron-El
Nov 3, 2011·Reproductive Biology and Endocrinology : RB&E·David B Gomes SobrinhoJosé G Franco
Mar 28, 2012·The Journal of Reproduction and Development·Masashi Takahashi
Jun 5, 2014·Journal of Assisted Reproduction and Genetics·Daniela P A F BragaEdson Borges
Dec 19, 2012·Fertility and Sterility·Kirstine KirkegaardHans Jakob Ingerslev
Aug 10, 2010·Reproductive Biomedicine Online·P L Wale, D K Gardner
Jul 13, 2012·The Cochrane Database of Systematic Reviews·Stephan BontekoeSebastiaan Mastenbroek
Jun 30, 2018·Molecular Reproduction and Development·Flavia R O de Barros, Fabíola F Paula-Lopes
Feb 6, 2019·Molecular Reproduction and Development·Priscila Ramos-IbeasAlfonso Gutiérrez-Adán
Sep 13, 2018·Zygote : the Biology of Gametes and Early Embryos·Camila M CavalcantiVicente J F Freitas
Sep 5, 2020·Molecular Reproduction and Development·Yu-Guo YuanIl-Keun Kong
Sep 24, 2019·Zygote : the Biology of Gametes and Early Embryos·R Sciorio, G D Smith
Jul 19, 2017·Journal of Assisted Reproduction and Genetics·Ioannis A SfontourisTryfon G Lainas
Oct 30, 2020·Antioxidants & Redox Signaling·Jing Lin, Ling Wang
Jan 28, 2021·Antioxidants·Pascale May-PanloupPascal Reynier
Feb 25, 2021·Zygote : the Biology of Gametes and Early Embryos·Nasser GhanemAshraf Hesham Barkawi

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