PMID: 6980194Jan 1, 1982Paper

In vitro effect of ethanol on subpopulations of human blood mononuclear cells

International Archives of Allergy and Applied Immunology
N E Gilhus, R Matre

Abstract

Mononuclear cells from 10 healthy blood donors were incubated with ethanol at 37 degrees C for 30 min. An ethanol concentration of 10.0 g/l reduced the percentage of active E rosette-forming cells (E RFC) from 25.0 +/- 12.1 to 16.2 +/- 8.7, and the percentage of total E RFC from 70.3 +/- 8.5 to 59.7 +/- 13.5 (p less than 0.01 for both). The percentage of cells with phagocytizing capacity was reduced from 11.7 +/- 5.4 to 7.0 +/- 5.0 by the ethanol treatment (p less than 0.01). Incubation with ethanol at a concentration of 1.0 g/l also significantly reduced the number of active and total E RFC and of phagocytizing cells. Ethanol at a concentration of 0.1 g/l did not influence these cell subpopulations. The number of EA RFC and EAC RFC were not influenced by ethanol.

Citations

Sep 1, 1991·Journal of Clinical Immunology·R T CookM Noel
Jan 1, 1983·International Journal of Immunopharmacology·N E Gilhus
Jan 29, 2003·Alcohol·Regina S Robinson, Leonard L Seelig
Sep 1, 1989·APMIS : Acta Pathologica, Microbiologica, Et Immunologica Scandinavica·H Mørland, B Mørland
May 26, 2001·The American Journal of Gastroenterology·P SinghS Bank
Aug 1, 1987·Scandinavian Journal of Immunology·B Mørland, J Mørland
Nov 1, 1995·The International Journal of the Addictions·J W Smith
Jun 1, 1994·Clinical and Experimental Immunology·T E Kruger, T R Jerrells
May 23, 2002·Immunopharmacology and Immunotoxicology·Mei-Ping ChangDean C Norman
Apr 1, 1985·Archives of Biochemistry and Biophysics·J R FarleyK H Lau

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