PMID: 2116755Apr 1, 1990Paper

In vitro effect of synthetic flavanoids on astrovirus infection

Antiviral Research
F SupertiG Donelli

Abstract

In this study we investigated the activity of halogeno-, cyano- and amidino-isoflavenes, isoflavans and flavans on the multiplication of human astroviruses. These are naked small round viruses which have been recognized as causative agents of human gastroenteritis, and whose capsid proteins are similar to those of picornaviruses. Although all drugs tested caused a dose-dependent reduction of viral antigen synthesis as monitored by immunofluorescence, the chloro derivatives were the most effective.

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Citations

Dec 1, 1992·Journal of Medical Virology·G DonelliM L Marziano
Jan 1, 1991·Journal of Pharmaceutical and Biomedical Analysis·M G QuagliaC Conti
Jan 1, 1992·Antimicrobial Agents and Chemotherapy·C ContiN Orsi
Oct 4, 2014·Clinical Microbiology Reviews·Albert BoschSusana Guix
Jul 3, 2021·Viruses·Nicole Wildi, Torsten Seuberlich

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