In Vitro Effect of Zingiber officinale Extract on Growth of Streptococcus mutans and Streptococcus sanguinis

International Journal of Dentistry
Arash AziziShirin Lawaf

Abstract

Background and Objectives. Tooth decay is an infectious disease of microbial origin. Considering the increasing prevalence of antibiotic resistance due to their overuse and also their side effects, medicinal plants are now considered for use against bacterial infections. This study aimed to assess the effects of different concentrations of Zingiber officinale extract on proliferation of Streptococcus mutans and Streptococcus sanguinis in vitro. Materials and Methods. In this experimental study, serial dilutions of the extract were prepared in two sets of 10 test tubes for each bacterium (total of 20). Standard amounts of bacterial suspension were added; 100ƛ of each tube was cultured on prepared solid agar plates and incubated at 37°C for 24 hours. Serial dilutions of the extract were prepared in another 20 tubes and 100ƛ of each tube was added to blood agar culture medium while being prepared. The mixture was transferred to the plates. The bacteria were inoculated on plates and incubated as described. Results. The minimum inhibitory concentration (MIC) was 0.02 mg/mL for S. mutans and 0.3 mg/mL for S. sanguinis. The minimum bactericidal concentration (MBC) was 0.04 mg for S. mutans and 0.6 mg for S. sanguinis. Conclusion. Zing...Continue Reading

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Citations

Aug 16, 2016·Photodiagnosis and Photodynamic Therapy·Arash AziziShirin Lawaf
Nov 12, 2016·Applied and Environmental Microbiology·Ian B StanawayElaine M Faustman
Mar 20, 2020·Journal of Biomolecular Structure & Dynamics·Laleh Babaeekhou, Maryam Ghane
Nov 12, 2020·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Gianmaria Fabrizio FerrazzanoTiziana Cantile
Jan 15, 2021·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fajar PrasetyaHadi Kuncoro

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