PMID: 2111724May 1, 1990Paper

In-vitro evaluation of a dual oxygen saturation/hematocrit intravascular fiberoptic catheter

Biomedical Instrumentation & Technology
Y MendelsonY Wang

Abstract

The authors describe the results of an in-vitro evaluation of a prototype new three-fiber intravascular fiberoptic catheter that is suitable for in-vivo measurement of mixed venous oxygen saturation and hematocrit simultaneously. The catheter consists of a single source and two unequally spaced (near and far) detecting fibers. The study showed that the ratio of backscattered light intensities measured at an isobestic wavelength by the two detecting fibers (IRnear/IRfar) can be used as a correcting factor for reducing the dependence of oxygen saturation measurements on hematocrit and also as a means for measuring hematocrit independently. The ability to measure hematocrit in vivo is important in critical care situations where fluids are administered intravenously and blood transfusions are performed routinely. Therefore, the purpose of this study was to investigate the quantitative effect of variations in red blood cell volume induced by changing the pH of the blood. The IRnear/IRfar ratio was found to be affected by variations in bicarbonate ion and carbon dioxide concentrations. The reflected light intensity detected by the catheter was found to be significantly more sensitive to changes in red blood cell volume induced by var...Continue Reading

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery
E P ProkopakisE S Helidonis
Pflügers Archiv : European journal of physiology
M L LandsmanW G Zijlstra
Annals of Biomedical Engineering
J M SchmittJ D Meindl
© 2021 Meta ULC. All rights reserved