PMID: 7537291Jan 1, 1995Paper

In vitro fertilization neonates transferred to neonatal medicine. Mid-and long-term outcome in 99 families

Journal de gynécologie, obstétrique et biologie de la reproduction
M Monset-CouchardJ P Relier

Abstract

To assess the physical and neurodevelopmental status of children born after in vitro fertilization (IVF) as well as the family condition. Follow-up study including physical and developmental examination in available families, and/or interviews of parents/pediatricians/teachers/social workers. The Port-Royal neonatal intensive care unit and follow-up clinic. From 1.1.1987 to 31.12.1992, in 32 single, 71 twin, 28 triple, and one quadruple pregnancies resulting from IVF (total 132), one or more neonates were admitted to the Port-Royal NICU. The outcome is presented for the 99 families followed longer than two years (199 neonates, 166/199 born prematurely). Neurological sequelae (minor, moderate, major), developmental quotients, school level, behavioral disturbances, family conditions. From 21 singletons (2 deaths, 1 lost), 18 survivors were followed: 17 were normal above 2 years (10 above 3 years went to school), 1 had a severe cerebral palsy with low IQ. From 57 twin pregnancies (7 fetal and 9 neonatal deaths), the 98 survivors were followed: 78 were normal above 2 years (65 above 3 years went to school), 20 had some neuro-developmental deficits (of 14 above 3 years, 12 went to school); 25 families had had or still had problems (...Continue Reading

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