In vitro flow experiments for determination of optimal geometry of total cavopulmonary connection for surgical repair of children with functional single ventricle

Journal of the American College of Cardiology
S SharmaA P Yoganathan

Abstract

This study sought to evaluate the effect of offsetting cavopulmonary connections at varying pulmonary flow ratios to determine the optimal geometry of the connection. Previous investigators have demonstrated energy conservation within the streamlined contours of the total cavopulmonary connection compared with that of the atriopulmonary connection. However, their surgical design of connecting the two cavae directly opposite each other may result in high energy losses. Others have introduced a unidirectional connection with some advantages but with concerns about the formation of arteriovenous malformation in the lung excluded from hepatic venous return. Thus, an optimal surgical design has not been determined. In the present models, the caval connections were offset through a range of 0.0 to 2.0 diameters by 0.5 superior cava diameter increments. Flow ratios were fixed for superior and inferior cavae and varied for right and left pulmonary arteries as 70:30, 60:40, 50:50, 40:60 and 30:70 to stimulate varying lung resistance. Pressure measurements and flow visualization were done at steady flows of 2, 4 and 6 liters/min to stimulate rest and exercise. Our data show that the energy losses at the 0.0-diameter offset were double th...Continue Reading

References

Aug 1, 1991·The Annals of Thoracic Surgery·J M PearlR G Williams
Oct 1, 1973·The Journal of Thoracic and Cardiovascular Surgery·G KreutzerJ P Laura
May 1, 1971·Thorax·F Fontan, E Baudet
Nov 1, 1995·Journal of Biomechanical Engineering·Y H KimA P Yoganathan

❮ Previous
Next ❯

Citations

Nov 10, 2004·Pediatric Cardiology·R J Ascuitto, N T Ross-Ascuitto
Mar 17, 2006·Pediatric Cardiology·K R MoyleT L Gentles
Mar 18, 2005·Biomechanics and Modeling in Mechanobiology·Francesco Migliavacca, Gabriele Dubini
Nov 30, 2000·Current Treatment Options in Cardiovascular Medicine·P S Rao
May 28, 2005·The Annals of Thoracic Surgery·Diane A de ZélicourtAjit P Yoganathan
Oct 30, 1999·The Annals of Thoracic Surgery·A E EnsleyA P Yoganathan
Oct 30, 1999·The Annals of Thoracic Surgery·W I DouglasE L Bove
Dec 10, 1999·The Annals of Thoracic Surgery·V K TamK Murphy
Apr 17, 2002·Journal of Biomechanics·G BolzonG D'Avenio
Jun 17, 2000·European Journal of Cardio-thoracic Surgery : Official Journal of the European Association for Cardio-thoracic Surgery·P G WalkerK G Watterson
Apr 9, 2013·Interactive Cardiovascular and Thoracic Surgery·Kalpi DesaiAjit P Yoganathan
Mar 31, 2005·Journal of Biomechanical Engineering·David FrakesAjit Yoganathan
Jul 8, 2008·Journal of Biomechanical Engineering·Hiroumi D KitajimaAjit P Yoganathan
May 13, 2010·Journal of Biomechanical Engineering·Onur DurKerem Pekkan
Oct 22, 2008·American Journal of Physiology. Heart and Circulatory Physiology·Kartik S SundareswaranAjit P Yoganathan
Jun 6, 2014·The International Journal of Cardiovascular Imaging·Timothy C Slesnick, Ajit P Yoganathan
Sep 4, 2007·Pediatric Cardiology·E L BoveG Dubini
Feb 11, 2014·The Journal of Thoracic and Cardiovascular Surgery·Christopher M HaggertyAjit P Yoganathan
Jun 16, 2012·The Journal of Thoracic and Cardiovascular Surgery·Kirk R KanterAjit P Yoganathan
Nov 18, 2011·The Journal of Thoracic and Cardiovascular Surgery·Kartik S SundareswaranAjit P Yoganathan
Jan 29, 2008·The Annals of Thoracic Surgery·Vibeke E HjortdalErik M Pedersen
Oct 25, 2006·The Journal of Thoracic and Cardiovascular Surgery·Hirohisa MurakamiTakuro Misaki
Jan 25, 2013·International Journal for Numerical Methods in Biomedical Engineering·Jinli DingFeng Wang
Jul 3, 1999·The Annals of Thoracic Surgery·A GerdesH H Sievers
Jul 1, 1998·The Annals of Thoracic Surgery·H H SieversG Pfister
Apr 7, 2015·Journal of Biomechanics·Alejandro Roldán-AlzateChristopher J François
Apr 4, 2006·The Journal of Thoracic and Cardiovascular Surgery·Diane A de ZélicourtAjit P Yoganathan
May 9, 2012·The Journal of Thoracic and Cardiovascular Surgery·Christopher M HaggertyAjit P Yoganathan

❮ Previous
Next ❯

Related Concepts

Related Feeds

Cardiology Journals

Discover the latest cardiology research in this collection of the top cardiology journals.